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Breaching the Great Wall: Peptidoglycan and Microbial Interactions

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Date 2006 Aug 9
PMID 16894338
Citations 58
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Abstract

Once thought to be a process that occurred only in a few human pathogens, release of biologically active peptidoglycan fragments during growth by Gram-negative bacteria controls many types of bacterial interaction, including symbioses and interactions between microorganisms. This Perspective explores the role of peptidoglycan fragments in mediating a range of microbial-host interactions, and discusses the many systems in which peptidoglycan fragments released during bacterial growth might be active.

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