Development of Structure and Function in the Infant Brain: Implications for Cognition, Language and Social Behaviour

Overview

Journal Neurosci Biobehav Rev

Specialties Neurology
Psychology
Social Sciences

Date 2006 Aug 8

PMID 16890291

Citations 24

Authors

Sarah J Paterson

Sabine Heim

Jennifer Thomas Friedman

Naseem Choudhury

April A Benasich

Affiliations

Soon will be listed here.

Abstract

Recent advances in cognitive neuroscience have allowed us to begin investigating the development of both structure and function in the infant brain. However, despite the rapid evolution of technology, surprisingly few studies have examined the intersection between brain and behaviour over the first years of life. Even fewer have done so in the context of a particular research question. This paper aims to provide an overview of four domains that have been studied using techniques amenable to elucidating the brain/behaviour interface: language, face processing, object permanence, and joint attention, with particular emphasis on studies focusing on early development. The importance of the unique role of development and the interplay between structure and function is stressed throughout. It is hoped that this review will serve as a catalyst for further thinking about the substantial gaps in our understanding of the relationship between brain and behaviour across development. Further, our aim is to provide ideas about candidate brain areas that are likely to be implicated in particular behaviours or cognitive domains.

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References

McEvoy R, Rogers S, Pennington B . Executive function and social communication deficits in young autistic children. J Child Psychol Psychiatry. 1993; 34(4):563-78. DOI: 10.1111/j.1469-7610.1993.tb01036.x. View

Baldwin D . Infants' contribution to the achievement of joint reference. Child Dev. 1991; 62(5):875-90. View

Kraus N, McGee T, Carrell T, Zecker S, Nicol T, Koch D . Auditory neurophysiologic responses and discrimination deficits in children with learning problems. Science. 1996; 273(5277):971-3. DOI: 10.1126/science.273.5277.971. View

Stark R, Heinz J . Perception of stop consonants in children with expressive and receptive-expressive language impairments. J Speech Hear Res. 1996; 39(4):676-86. DOI: 10.1044/jshr.3904.676. View

McAnally K, Stein J . Auditory temporal coding in dyslexia. Proc Biol Sci. 1996; 263(1373):961-5. DOI: 10.1098/rspb.1996.0142. View

Galaburda A . Neuroanatomic basis of developmental dyslexia. Neurol Clin. 1993; 11(1):161-73. View

Taylor M, Edmonds G, McCarthy G, Allison T . Eyes first! Eye processing develops before face processing in children. Neuroreport. 2001; 12(8):1671-6. DOI: 10.1097/00001756-200106130-00031. View

Mundy P . Annotation: the neural basis of social impairments in autism: the role of the dorsal medial-frontal cortex and anterior cingulate system. J Child Psychol Psychiatry. 2003; 44(6):793-809. DOI: 10.1111/1469-7610.00165. View

Damasio A, Damasio H, Van Hoesen G . Prosopagnosia: anatomic basis and behavioral mechanisms. Neurology. 1982; 32(4):331-41. DOI: 10.1212/wnl.32.4.331. View

10.

Werker J, Tees R . Speech perception in severely disabled and average reading children. Can J Psychol. 1987; 41(1):48-61. DOI: 10.1037/h0084150. View

11.

Diamond A . The development and neural bases of memory functions as indexed by the AB and delayed response tasks in human infants and infant monkeys. Ann N Y Acad Sci. 1990; 608:267-309; discussion 309-17. DOI: 10.1111/j.1749-6632.1990.tb48900.x. View

12.

Peiffer A, Friedman J, Rosen G, Holly Fitch R . Impaired gap detection in juvenile microgyric rats. Brain Res Dev Brain Res. 2004; 152(2):93-8. DOI: 10.1016/j.devbrainres.2004.06.003. View

13.

Comi E, Annovazzi P, Silva A, Cursi M, Blasi V, Cadioli M . Visual evoked potentials may be recorded simultaneously with fMRI scanning: A validation study. Hum Brain Mapp. 2005; 24(4):291-8. PMC: 6871709. DOI: 10.1002/hbm.20087. View

14.

Liebenthal E, Ellingson M, Spanaki M, Prieto T, Ropella K, Binder J . Simultaneous ERP and fMRI of the auditory cortex in a passive oddball paradigm. Neuroimage. 2003; 19(4):1395-404. DOI: 10.1016/s1053-8119(03)00228-3. View

15.

de Haan M, Nelson C . Recognition of the mother's face by six-month-old infants: a neurobehavioral study. Child Dev. 1997; 68(2):187-210. View

16.

Snowling M, Goulandris N, Bowlby M, Howell P . Segmentation and speech perception in relation to reading skill: a developmental analysis. J Exp Child Psychol. 1986; 41(3):489-507. DOI: 10.1016/0022-0965(86)90006-8. View

17.

Larsen J, Hoien T, Lundberg I, ODEGAARD H . MRI evaluation of the size and symmetry of the planum temporale in adolescents with developmental dyslexia. Brain Lang. 1990; 39(2):289-301. DOI: 10.1016/0093-934x(90)90015-9. View

18.

Shallice T, Fletcher P, Frith C, Grasby P, Frackowiak R, Dolan R . Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature. 1994; 368(6472):633-5. DOI: 10.1038/368633a0. View

19.

Zaehle T, Wustenberg T, Meyer M, Jancke L . Evidence for rapid auditory perception as the foundation of speech processing: a sparse temporal sampling fMRI study. Eur J Neurosci. 2004; 20(9):2447-56. DOI: 10.1111/j.1460-9568.2004.03687.x. View

20.

Galaburda A, Menard M, Rosen G . Evidence for aberrant auditory anatomy in developmental dyslexia. Proc Natl Acad Sci U S A. 1994; 91(17):8010-3. PMC: 44534. DOI: 10.1073/pnas.91.17.8010. View