The Mycobacterium-specific Gene Rv2719c is DNA Damage Inducible Independently of RecA

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2006 Aug 4

PMID 16885473

Citations 12

Authors

Patricia C Brooks

Lisa F Dawson

Lucinda Rand

Elaine O Davis

Affiliations

Soon will be listed here.

Abstract

The mycobacterium-specific gene Rv2719c was found to be expressed primarily from a promoter that was clearly DNA damage inducible independently of RecA. Upstream of the transcriptional start site for this promoter, sequence motifs resembling those observed previously at the RecA-independent, DNA damage-inducible recA promoter were identified, and the -10 motif was demonstrated by mutational analysis in transcriptional fusion constructs to be important for expression of Rv2719c.

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