» Articles » PMID: 16878180

Optical Trapping

Overview
Journal Rev Sci Instrum
Date 2006 Aug 1
PMID 16878180
Citations 413
Authors
Affiliations
Soon will be listed here.
Abstract

Since their invention just over 20 years ago, optical traps have emerged as a powerful tool with broad-reaching applications in biology and physics. Capabilities have evolved from simple manipulation to the application of calibrated forces on-and the measurement of nanometer-level displacements of-optically trapped objects. We review progress in the development of optical trapping apparatus, including instrument design considerations, position detection schemes and calibration techniques, with an emphasis on recent advances. We conclude with a brief summary of innovative optical trapping configurations and applications.

Citing Articles

Optical tweezers in biomedical research - progress and techniques.

Yadav D, Savopol T J Med Life. 2025; 17(11):978-993.

PMID: 39781305 PMC: 11705474. DOI: 10.25122/jml-2024-0316.


Methods for Studying Motor-Driven Viral DNA Packaging in Bacteriophages phi29, Lambda, and T4 via Single DNA Molecule Manipulation and Rapid Solution Exchange.

Fizari M, Rawson B, Keller N, delToro D, Smith D Methods Mol Biol. 2024; 2881():293-327.

PMID: 39704950 DOI: 10.1007/978-1-0716-4280-1_15.


The role of temperature-induced effects generated by plasmonic nanostructures on particle delivery and manipulation: a review.

Kotsifaki D, Nic Chormaic S Nanophotonics. 2024; 11(10):2199-2218.

PMID: 39678096 PMC: 11636517. DOI: 10.1515/nanoph-2022-0014.


Optical trapping and manipulating with a transmissive and polarization-insensitive metalens.

Yang D, Zhang J, Zhang P, Liang H, Ma J, Li J Nanophotonics. 2024; 13(15):2781-2789.

PMID: 39635250 PMC: 11501135. DOI: 10.1515/nanoph-2023-0850.


Nonthermal fluctuations accelerate biomolecular motors.

Ariga T Biophys Rev. 2024; 16(5):605-612.

PMID: 39618792 PMC: 11604964. DOI: 10.1007/s12551-024-01238-x.


References
1.
Noji H, Yasuda R, Yoshida M, Kinosita Jr K . Direct observation of the rotation of F1-ATPase. Nature. 1997; 386(6622):299-302. DOI: 10.1038/386299a0. View

2.
Svoboda K, Schmidt C, Schnapp B, Block S . Direct observation of kinesin stepping by optical trapping interferometry. Nature. 1993; 365(6448):721-7. DOI: 10.1038/365721a0. View

3.
Lang M, Asbury C, Shaevitz J, Block S . An automated two-dimensional optical force clamp for single molecule studies. Biophys J. 2002; 83(1):491-501. PMC: 1302163. DOI: 10.1016/S0006-3495(02)75185-0. View

4.
Allemand J, Bensimon D, Croquette V . Stretching DNA and RNA to probe their interactions with proteins. Curr Opin Struct Biol. 2003; 13(3):266-74. DOI: 10.1016/s0959-440x(03)00067-8. View

5.
Perkins T, Smith D, Chu S . Direct observation of tube-like motion of a single polymer chain. Science. 1994; 264(5160):819-22. DOI: 10.1126/science.8171335. View