Investigation of Global Developmental Delay

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 2006 Jul 25

PMID 16861488

Citations 22

Authors

L McDonald

A Rennie

J Tolmie

P Galloway

R McWilliam

Affiliations

Soon will be listed here.

Abstract

The investigation of global developmental delay in preschool children varies between centres and between paediatricians. Following a literature search and review of the evidence base, guidelines were developed to assist in the assessment and management of such children presenting to secondary level services. Evidence supporting the use of genetic and biochemical investigations on a screening basis was found, but there was no evidence to support the use of metabolic investigations or neuroimaging in the absence of other positive findings on history or examination. Detailed history and examination are paramount in the assessment of children with global developmental delay. Investigations can be a useful adjunct in determining aetiology. Evidence based guidelines have been developed to assist doctors in the selection of appropriate investigations for this group of children.

Citing Articles

Metabolic Evaluation in Children aged 3 months to 2 years with Global Developmental Delay.

Gomes R, Bhat Y R, Kini S, Kini P, Shrikiran A, Suneel C Indian J Pediatr. 2023; 92(2):123-130.

PMID: 38082212 PMC: 11758175. DOI: 10.1007/s12098-023-04927-9.

Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay.

Settimo C, De Cola M, Pironti E, Muratore R, Giambo F, Alito A J Clin Med. 2023; 12(15).

PMID: 37568364 PMC: 10419390. DOI: 10.3390/jcm12154962.

Global Developmental Delay in Children with Full Mouth Rehabilitation: A Case Series.

Thimmegowda U, Chikkanarasaiah N, Athira P, Krishnamurthy N Int J Clin Pediatr Dent. 2023; 16(3):522-527.

PMID: 37496953 PMC: 10367283. DOI: 10.5005/jp-journals-10005-2605.

Implications of Early Diagnosis and Intervention in the Management of Neurodevelopmental Delay (NDD) in Children: A Systematic Review and Meta-Analysis.

Aldharman S, Al-Jabr K, Alharbi Y, Alnajar N, Alkhanani J, Alghamdi A Cureus. 2023; 15(5):e38745.

PMID: 37303321 PMC: 10248310. DOI: 10.7759/cureus.38745.

Brain Magnetic Resonance Imaging Findings in Patients with Developmental Delay in Addis Ababa, Ethiopia.

Balcha T, Woldeyohannes A, Neknek G Ethiop J Health Sci. 2022; 32(4):773-780.

PMID: 35950074 PMC: 9341008. DOI: 10.4314/ejhs.v32i4.14.

References

Shevell M, Majnemer A, Rosenbaum P, Abrahamowicz M . Etiologic yield of subspecialists' evaluation of young children with global developmental delay. J Pediatr. 2000; 136(5):593-8. DOI: 10.1067/mpd.2000.104817. View

Maclennan A . A template for defining a causal relation between acute intrapartum events and cerebral palsy: international consensus statement. BMJ. 1999; 319(7216):1054-9. PMC: 1116849. DOI: 10.1136/bmj.319.7216.1054. View

Essex C, Roper H . Lesson of the week: late diagnosis of Duchenne's muscular dystrophy presenting as global developmental delay. BMJ. 2001; 323(7303):37-8. PMC: 1120666. DOI: 10.1136/bmj.323.7303.37. View

Lewendon G, Kinra S, Nelder R, Cronin T . Should children with developmental and behavioural problems be routinely screened for lead?. Arch Dis Child. 2001; 85(4):286-8. PMC: 1718950. DOI: 10.1136/adc.85.4.286. View

Fitzpatrick D, Pearson P, Halpin S, Jackson P . A school based study of children with learning disability indicates poor levels of genetic investigation. J Med Genet. 2002; 39(4):e19. PMC: 1735099. DOI: 10.1136/jmg.39.4.e19. View

Yager J, Hartfield D . Neurologic manifestations of iron deficiency in childhood. Pediatr Neurol. 2002; 27(2):85-92. DOI: 10.1016/s0887-8994(02)00417-4. View

Battaglia A, Carey J . Diagnostic evaluation of developmental delay/mental retardation: An overview. Am J Med Genet C Semin Med Genet. 2003; 117C(1):3-14. DOI: 10.1002/ajmg.c.10015. View

Shevell M, Ashwal S, Donley D, Flint J, GINGOLD M, Hirtz D . Practice parameter: evaluation of the child with global developmental delay: report of the Quality Standards Subcommittee of the American Academy of Neurology and The Practice Committee of the Child Neurology Society. Neurology. 2003; 60(3):367-80. DOI: 10.1212/01.wnl.0000031431.81555.16. View

de Vries B, Winter R, Schinzel A, van Ravenswaaij-Arts C . Telomeres: a diagnosis at the end of the chromosomes. J Med Genet. 2003; 40(6):385-98. PMC: 1735506. DOI: 10.1136/jmg.40.6.385. View

10.

Weber P, Scholl S, Baumgartner E . Outcome in patients with profound biotinidase deficiency: relevance of newborn screening. Dev Med Child Neurol. 2004; 46(7):481-4. DOI: 10.1017/s0012162204000799. View

11.

Grunewald S, Champion M, Leonard J, Schaper J, Morris A . Biotinidase deficiency: a treatable leukoencephalopathy. Neuropediatrics. 2004; 35(4):211-6. DOI: 10.1055/s-2004-821080. View

12.

Schaefer G, Bodensteiner J . Evaluation of the child with idiopathic mental retardation. Pediatr Clin North Am. 1992; 39(4):929-43. DOI: 10.1016/s0031-3955(16)38381-x. View

13.

Levy S, Hyman S . Pediatric assessment of the child with developmental delay. Pediatr Clin North Am. 1993; 40(3):465-77. DOI: 10.1016/s0031-3955(16)38544-3. View

14.

Newton R, Wraith J . Investigation of developmental delay. Arch Dis Child. 1995; 72(5):460-5. PMC: 1511114. DOI: 10.1136/adc.72.5.460. View

15.

Majnemer A, Shevell M . Diagnostic yield of the neurologic assessment of the developmentally delayed child. J Pediatr. 1995; 127(2):193-9. DOI: 10.1016/s0022-3476(95)70294-6. View

16.

Curry C, Stevenson R, Aughton D, Byrne J, Carey J, Cassidy S . Evaluation of mental retardation: recommendations of a Consensus Conference: American College of Medical Genetics. Am J Med Genet. 1997; 72(4):468-77. DOI: 10.1002/(sici)1096-8628(19971112)72:4<468::aid-ajmg18>3.0.co;2-p. View

17.

Shevell M . The evaluation of the child with a global developmental delay. Semin Pediatr Neurol. 1998; 5(1):21-6. DOI: 10.1016/s1071-9091(98)80014-4. View

18.

Schaefer G, Bodensteiner J . Radiological findings in developmental delay. Semin Pediatr Neurol. 1998; 5(1):33-8. DOI: 10.1016/s1071-9091(98)80016-8. View

19.

Sheth R . Electroencephalogram in developmental delay: specific electroclinical syndromes. Semin Pediatr Neurol. 1998; 5(1):45-51. DOI: 10.1016/s1071-9091(98)80018-1. View

20.

Gringras P . Choice of medical investigations for developmental delay: a questionnaire survey. Child Care Health Dev. 1998; 24(4):267-76. DOI: 10.1111/j.1365-2214.1998.tb00946.x. View