The Effect of Prior Biopsy Scheme on Prostate Cancer Detection for Repeat Biopsy Population: Results of the 14-core Prostate Biopsy Technique

Overview

Journal Int Urol Nephrol

Publisher Springer

Specialty Nephrology

Date 2006 Jul 13

PMID 16835725

Citations 8

Authors

Saadettin Yilmaz Eskicorapci

Fuad Guliyev

Ekrem Islamoglu

Ali Ergen

Haluk Ozen

Affiliations

Soon will be listed here.

Abstract

Objectives: To evaluate the diagnostic performance of 14-core repeat biopsy protocol and the impact of prior biopsy scheme on repeat prostate biopsy group.

Methods: 211 patients had repeat biopsy using 14-core protocol consisting of 10-core peripheral zone (classical sextant+4 lateral peripheral cores) and 4-core transitional zone (TZ) biopsies. The diagnostic yield was determined both in patients who had previously undergone sextant or 10-core biopsy protocol.

Results: Overall cancer detection rate was 25.6%. 14-core biopsy technique detected cancer in 36.1 and 18.7% of the patients who had a previous sextant biopsy and 10-core biopsy protocol, respectively (P = 0.005). Patients with and without high-grade prostatic intraepithelial neoplasia (HGPIN) in the previous sextant biopsy had 56.5 and 28.3% cancer detection rates on the subsequent extended biopsy, respectively (P = 0.017) Patients who had previous 10-core biopsy with and without HGPIN revealed 22.9 and 17.2% cancer detection rates, respectively (P = 0.465) Additional four lateral peripheral cores detected 33% (3/30) and 17% (4/24) of cancers in patients with previous sextant and 10-core biopsy, respectively. 3.7% of the patients had tumor only in the TZ and none of them had prior extended biopsy.

Conclusions: The yield of extended 14-core repeat biopsy protocol was higher in patients with previous negative sextant biopsy compared to the patients with previous negative 10-core biopsy. HGPIN history found on previous sextant biopsy was a strong cancer predictor on repeat biopsy; same was not true for the patients with previous 10-core biopsy. The yield of lateral peripheral cores and TZ biopsies were lower in patients with prior negative extended biopsy.

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References

Hong Y, Lai F, Chon C, McNeal J, Presti Jr J . Impact of prior biopsy scheme on pathologic features of cancers detected on repeat biopsies. Urol Oncol. 2004; 22(1):7-10. DOI: 10.1016/S1078-1439(03)00147-9. View

Lopez-Corona E, Ohori M, Scardino P, Reuter V, Gonen M, Kattan M . A nomogram for predicting a positive repeat prostate biopsy in patients with a previous negative biopsy session. J Urol. 2003; 170(4 Pt 1):1184-8. DOI: 10.1097/01.ju.0000087451.64657.fa. View

Presti Jr J . Prostate biopsy: how many cores are enough?. Urol Oncol. 2003; 21(2):135-40. DOI: 10.1016/s1078-1439(03)00006-1. View

Herawi M, Kahane H, Cavallo C, Epstein J . Risk of prostate cancer on first re-biopsy within 1 year following a diagnosis of high grade prostatic intraepithelial neoplasia is related to the number of cores sampled. J Urol. 2006; 175(1):121-4. DOI: 10.1016/S0022-5347(05)00064-9. View

Eskicorapci S, Baydar D, Akbal C, Sofikerim M, Gunay M, Ekici S . An extended 10-core transrectal ultrasonography guided prostate biopsy protocol improves the detection of prostate cancer. Eur Urol. 2004; 45(4):444-8. DOI: 10.1016/j.eururo.2003.11.024. View

Hodge K, McNeal J, Terris M, Stamey T . Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol. 1989; 142(1):71-4; discussion 74-5. DOI: 10.1016/s0022-5347(17)38664-0. View

Lui P, Terris M, McNeal J, Stamey T . Indications for ultrasound guided transition zone biopsies in the detection of prostate cancer. J Urol. 1995; 153(3 Pt 2):1000-3. View

Stewart C, Leibovich B, Weaver A, Lieber M . Prostate cancer diagnosis using a saturation needle biopsy technique after previous negative sextant biopsies. J Urol. 2001; 166(1):86-91; discussion 91-2. View

Carter H, Epstein J, Chan D, Fozard J, Pearson J . Recommended prostate-specific antigen testing intervals for the detection of curable prostate cancer. JAMA. 1997; 277(18):1456-60. View

10.

Applewhite J, Matlaga B, McCULLOUGH D . Results of the 5 region prostate biopsy method: the repeat biopsy population. J Urol. 2002; 168(2):500-3. View

11.

Djavan B, Ravery V, Zlotta A, Dobronski P, Dobrovits M, Fakhari M . Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop?. J Urol. 2001; 166(5):1679-83. View

12.

Eskicorapci S, Karabulut E, Turkeri L, Baltaci S, Cal C, Toktas G . Validation of 2001 Partin tables in Turkey: a multicenter study. Eur Urol. 2005; 47(2):185-9. DOI: 10.1016/j.eururo.2004.08.002. View

13.

Borboroglu P, Comer S, Riffenburgh R, Amling C . Extensive repeat transrectal ultrasound guided prostate biopsy in patients with previous benign sextant biopsies. J Urol. 1999; 163(1):158-62. View

14.

Eskicorapci S, Guliyev F, Akdogan B, Dogan H, Ergen A, Ozen H . Individualization of the biopsy protocol according to the prostate gland volume for prostate cancer detection. J Urol. 2005; 173(5):1536-40. DOI: 10.1097/01.ju.0000154242.60413.3d. View

15.

Babaian R, Toi A, Kamoi K, Troncoso P, Sweet J, Evans R . A comparative analysis of sextant and an extended 11-core multisite directed biopsy strategy. J Urol. 1999; 163(1):152-7. View

16.

Eskew L, Bare R, McCullough D . Systematic 5 region prostate biopsy is superior to sextant method for diagnosing carcinoma of the prostate. J Urol. 1997; 157(1):199-202; discussion 202-3. View

17.

Keetch D, Catalona W . Prostatic transition zone biopsies in men with previous negative biopsies and persistently elevated serum prostate specific antigen values. J Urol. 1995; 154(5):1795-7. View

18.

Rabbani F, Stroumbakis N, Kava B, Cookson M, Fair W . Incidence and clinical significance of false-negative sextant prostate biopsies. J Urol. 1998; 159(4):1247-50. View

19.

Chon C, Lai F, McNeal J, Presti Jr J . Use of extended systematic sampling in patients with a prior negative prostate needle biopsy. J Urol. 2002; 167(6):2457-60. View