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[A Case of Normal-tension Glaucoma with Impaired Eye Movements in a Young Patient]

Overview
Specialty Ophthalmology
Date 2006 Jul 1
PMID 16808164
Citations 2
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Abstract

Background: We report a case of normal-tension glaucoma(NTG) with impaired eye movements in a young patient.

Case: A 22-year-old man with enlarged optic disc cuppings and visual field defects was suspected to have NTG, and was found, upon examination, to have impaired eye movements. Intraocular pressure recordings, including diurnal variation, were under 21 mmHg. Gonioscopic findings were normal. Magnetic resonance image(MRI) showed no particular findings. The patient was diagnosed with NTG. Using the 123I-iodoamphetamine single photon emission computed tomography (123I-IMP SPECT), decreased cerebral blood flow was detected in the patient's occipital lobe and an electro-oculogram showed impaired eye movements during smooth pursuit. The patient's visual field defects have increased over the last two years, but, no accompanying change in his eye movements has been observed.

Conclusion: The patient in this case has NTG with impaired eye movements and decreased cerebral blood flow suggesting that some disorder of the central nervous system may be one of the causative mechanisms of NTG.

Citing Articles

Arterial spin labeling fMRI measurements of decreased blood flow in primary visual cortex correlates with decreased visual function in human glaucoma.

Duncan R, Sample P, Bowd C, Weinreb R, Zangwill L Vision Res. 2012; 60:51-60.

PMID: 22465941 PMC: 3340501. DOI: 10.1016/j.visres.2012.03.012.


Retinotopic organization of primary visual cortex in glaucoma: Comparing fMRI measurements of cortical function with visual field loss.

Duncan R, Sample P, Weinreb R, Bowd C, Zangwill L Prog Retin Eye Res. 2006; 26(1):38-56.

PMID: 17126063 PMC: 1940234. DOI: 10.1016/j.preteyeres.2006.10.001.