Novel Recombinant Norovirus Causing Outbreaks of Gastroenteritis in Santiago, Chile
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Capsid and polymerase (RdRp) genes of 13 norovirus outbreak strains from Chile were compared. The genes sequences were discordant for five strains, and recombination was confirmed for two of them by amplification of a 1,360-bp gene segment containing a fragment of both genes. These strains belonged to a novel genogroup by RdRp sequence and to genogroup GII/3 by capsid sequence. Determining the clinical and epidemiological impact of human calicivirus recombination will require future studies.
Hwang H, Puth S, Tan W, Verma V, Jeong K, Lee S Hum Vaccin Immunother. 2018; 14(9):2194-2202.
PMID: 29781755 PMC: 6183199. DOI: 10.1080/21645515.2018.1472185.
A Multi-Site Study of Norovirus Molecular Epidemiology in Australia and New Zealand, 2013-2014.
Lim K, Hewitt J, Sitabkhan A, Eden J, Lun J, Levy A PLoS One. 2016; 11(4):e0145254.
PMID: 27116221 PMC: 4846056. DOI: 10.1371/journal.pone.0145254.
Environmental Surveillance of Genogroup I and II Noroviruses in Shandong Province, China in 2013.
Tao Z, Xu M, Lin X, Wang H, Song L, Wang S Sci Rep. 2015; 5:17444.
PMID: 26616566 PMC: 5378908. DOI: 10.1038/srep17444.
ORyan M, Vidal R, Del Canto F, Salazar J, Montero D Hum Vaccin Immunother. 2015; 11(3):584-600.
PMID: 25715048 PMC: 4514277. DOI: 10.1080/21645515.2015.1011019.
Evolutionary phylodynamics of Korean noroviruses reveals a novel GII.2/GII.10 recombination event.
Truong T, Than V, Kim W PLoS One. 2014; 9(12):e113966.
PMID: 25500567 PMC: 4264735. DOI: 10.1371/journal.pone.0113966.