Synthesis and Analgesic Activity of 2-phenoxybenzoic Acid and N-phenylanthranilic Acid Hydrazides

Overview

Journal Biol Pharm Bull

Specialty Biochemistry

Date 2006 Jun 7

PMID 16755013

Citations 10

Authors

Ali Almasirad

Rohollah Hosseini

Hassan Jalalizadeh

Zohreh Rahimi-Moghaddam

Nazila Abaeian

Maryam Janafrooz

Mohammad Abbaspour

Vahid Ziaee

Afshin Dalvandi

Abbas Shafiee

Affiliations

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Abstract

A series of 2-phenoxybenzoic acid and N-phenylanthranilic acid hydrazides were synthesized and evaluated for their analgesic activities. Several compounds were significantly more potent than mefenamic acid and diclofenac sodium in abdominal constriction and formalin tests.

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