Epidermal Basement Membrane: Its Molecular Organization and Blistering Disorders

Overview

Journal Connect Tissue Res

Publisher Informa Healthcare

Date 2006 Jun 7

PMID 16754511

Citations 11

Authors

Takuji Masunaga

Affiliations

Soon will be listed here.

Abstract

The epidermal basement membrane is a specialized structure localized between the epidermis and the dermis. Recent studies have elucidated the biological roles of the basement membrane and its pathophysiological involvement in bullous diseases. To understand the functions of the basement membrane, it is essential to have clear and precise information regarding the ultrastructural molecular organization of the epidermal basement membrane. Immunoelectron microscopy is a powerful technique and the only method available for the clarification of the ultrastructural localization or orientation of molecules. This review summarizes the latest information regarding the molecular organization of the epidermal basement membrane as determined by immunoelectron microscopy as well as the blistering diseases that occur in the epidermal basement membrane zone.

Citing Articles

: Next-generation sequencing sheds light on Witkop's classification.

Bloch-Zupan A, Rey T, Jimenez-Armijo A, Kawczynski M, Kharouf N, de La Dure-Molla M Front Physiol. 2023; 14:1130175.

PMID: 37228816 PMC: 10205041. DOI: 10.3389/fphys.2023.1130175.

Candidate gene sequencing reveals mutations causing hypoplastic amelogenesis imperfecta.

Kim Y, Seymen F, Kang J, Koruyucu M, Tuloglu N, Bayrak S Clin Oral Investig. 2018; 23(3):1481-1487.

PMID: 30120606 PMC: 6378126. DOI: 10.1007/s00784-018-2577-9.

Identification of a Novel Mutation of Gene in a Lybian Patient with Hereditary Epidermolysis Bullosa by Whole Exome Sequencing.

Laroussi N, Messaoud O, Chargui M, Ben Fayala C, Elahlafi A, Mokni M Ann Dermatol. 2017; 29(2):243-246.

PMID: 28392661 PMC: 5383759. DOI: 10.5021/ad.2017.29.2.243.

Novel ITGB6 mutation in autosomal recessive amelogenesis imperfecta.

Seymen F, Lee K, Koruyucu M, Gencay K, Bayram M, Tuna E Oral Dis. 2014; 21(4):456-61.

PMID: 25431241 PMC: 4440386. DOI: 10.1111/odi.12303.

Review: dermatitis herpetiformis.

Mendes F, Hissa-Elian A, de Abreu M, Goncalves V An Bras Dermatol. 2013; 88(4):594-9.

PMID: 24068131 PMC: 3760935. DOI: 10.1590/abd1806-4841.20131775.