Effect of Virus Infection on the Stability and Synthesis of Actinomycin-resistant Ribonucleic Acid in Baby-hamster Kidney Cells

Overview

Journal Biochem J

Specialty Biochemistry

Date 1967 Dec 1

PMID 16742575

Citations 1

Authors

S J Martin

F Brown

Affiliations

Soon will be listed here.

Abstract

1. The sucrose-gradient pattern of (32)P-labelled RNA synthesized in actinomycintreated baby-hamster kidney cells infected with foot-and-mouth-disease virus depends greatly on the period of labelling. 2. Fractions are formed in infected cells that sediment at 12-20s and have the same base composition as similar fractions found in non-infected cells that have been treated with actinomycin. 3. In the presence of guanidine, which completely inhibits viral RNA synthesis, these fractions are labelled to a greater extent than in non-infected cells.

Citing Articles

Synthesis of ribonucleic acid in baby-hamster kidney cells in the presence of actinomycin D.

Martin S, Brown F Biochem J. 1967; 105(3):979-85.

PMID: 16742574 PMC: 1198416. DOI: 10.1042/bj1050979.

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