Imaging Cerebral Blood Flow Through the Intact Rat Skull with Temporal Laser Speckle Imaging

Overview

Journal Opt Lett

Specialty Ophthalmology

Date 2006 May 27

PMID 16729083

Citations 47

Authors

Pengcheng Li

SongLin Ni

Li Zhang

Shaoqun Zeng

Qingming Luo

Affiliations

Soon will be listed here.

Abstract

We discovered that laser speckle temporal contrast analysis (LSTCA) is able to access the two-dimensional (2D) cerebral blood flow velocity and vessel structure through the intact rat skull. It is demonstrated that LSTCA can significantly suppress the influence of the laser speckle from the stationary structure, such as the skull, and thus reveal the blood flow and morphology of blood vessels through the laser speckle images recorded from the intact rat skull.

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