» Articles » PMID: 16718804

Functional Oesophago-gastric Junction Imaging

Overview
Specialty Gastroenterology
Date 2006 May 24
PMID 16718804
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

Despite its role in disease there is still no definitive method to assess oesophago-gastric junction competence (OGJ). Traditionally the OGJ has been assessed using manometry with lower oesophageal sphincter pressure as the indicator. More recently this has been shown not to be a very reliable marker of sphincter function and competence against reflux. Disorders such as gastro-oesophageal reflux disease and to a lesser extend achalasia still effects a significant number of patients. This review looks at using a new technique known as impedance planimetry to profile the geometry and pressure in the OGJ during distension of a bag. The data gathered can be reconstructed into a dynamic representation of OGJ action. This has been shown to provide a useful representation of the OGJ and to show changes to the competence of the OGJ in terms of compliance and distensibility as a result of endoluminal therapy.

Citing Articles

What Is the Future of Impedance Planimetry in Gastroenterology?.

Gregersen H, Lo K J Neurogastroenterol Motil. 2018; 24(2):166-181.

PMID: 29605974 PMC: 5885717. DOI: 10.5056/jnm18013.


Emerging Roles of the Endolumenal Functional Lumen Imaging Probe in Gastrointestinal Motility Disorders.

Ata-Lawenko R, Lee Y J Neurogastroenterol Motil. 2016; 23(2):164-170.

PMID: 28013295 PMC: 5383111. DOI: 10.5056/jnm16171.


Microdissection of Human Esophagogastric Junction Wall with Phase-contrast X-ray CT Imaging.

Zhang J, Zhou G, Tian D, Lin R, Peng G, Su M Sci Rep. 2015; 5:13831.

PMID: 26346099 PMC: 4561904. DOI: 10.1038/srep13831.


Functional lumen imaging of the gastrointestinal tract.

Lottrup C, Gregersen H, Liao D, Fynne L, Frokjaer J, Krogh K J Gastroenterol. 2015; 50(10):1005-16.

PMID: 25980822 DOI: 10.1007/s00535-015-1087-7.


Clinical potential of naloxegol in the management of opioid-induced bowel dysfunction.

Poulsen J, Brock C, Olesen A, Nilsson M, Drewes A Clin Exp Gastroenterol. 2014; 7:345-58.

PMID: 25278772 PMC: 4179399. DOI: 10.2147/CEG.S52097.


References
1.
Assentoft J, Gregersen H, OBrien Jr W . Determination of biomechanical properties in guinea pig esophagus by means of high frequency ultrasound and impedance planimetry. Dig Dis Sci. 2000; 45(7):1260-6. DOI: 10.1023/a:1005579214416. View

2.
Biancani P, Barwick K, Selling J, McCallum R . Effects of acute experimental esophagitis on mechanical properties of the lower esophageal sphincter. Gastroenterology. 1984; 87(1):8-16. View

3.
Villadsen G, Storkholm J, Zachariae H, HENDEL L, Bendtsen F, Gregersen H . Oesophageal pressure-cross-sectional area distributions and secondary peristalsis in relation to subclassification of systemic sclerosis. Neurogastroenterol Motil. 2001; 13(3):199-210. DOI: 10.1046/j.1365-2982.2001.00259.x. View

4.
Jenkinson A, Scott S, Yazaki E, Fusai G, Walker S, Kadirkamanathan S . Compliance measurement of lower esophageal sphincter and esophageal body in achalasia and gastroesophageal reflux disease. Dig Dis Sci. 2001; 46(9):1937-42. DOI: 10.1023/a:1010639232137. View

5.
Barlow J, Gregersen H, Thompson D . Identification of the biomechanical factors associated with the perception of distension in the human esophagus. Am J Physiol Gastrointest Liver Physiol. 2002; 282(4):G683-9. DOI: 10.1152/ajpgi.00134.2001. View