Calcium and Vitamin D in the Prevention and Treatment of Osteoporosis - a Clinical Update

Overview

Journal J Intern Med

Specialty General Medicine

Date 2006 May 18

PMID 16704554

Citations 42

Authors

S Boonen

D Vanderschueren

P Haentjens

P Lips

Affiliations

Soon will be listed here.

Abstract

Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day(-1) vitamin D is complemented with a dose of 1000-1200 mg day(-1) elemental calcium. Compliance is also key to optimizing clinical efficacy.

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