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The Montreal Classification of Inflammatory Bowel Disease: Controversies, Consensus, and Implications

Overview
Journal Gut
Specialty Gastroenterology
Date 2006 May 16
PMID 16698746
Citations 1121
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Abstract

In recent years, investigators have readdressed the complex issues involved in the classification of inflammatory bowel diseases. In 2003, a Working Party of investigators with an interest in the issues involved in disease subclassification was formed with the aim of summarising recent developments in disease classification and establishing an integrated clinical, molecular, and serological classification of inflammatory bowel disease. The results of the Working Party were reported at the 2005 Montreal World Congress of Gastroenterology. Here we highlight the key issues that have emerged from discussions of the Montreal Working Party and the relevance to clinical practice and research activities.

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References
1.
Bairead E, Harmon D, Curtis A, Kelly Y, OLeary C, Gardner M . Association of NOD2 with Crohn's disease in a homogenous Irish population. Eur J Hum Genet. 2003; 11(3):237-44. DOI: 10.1038/sj.ejhg.5200954. View

2.
Targan S, Landers C, Yang H, Lodes M, Cong Y, Papadakis K . Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology. 2005; 128(7):2020-8. DOI: 10.1053/j.gastro.2005.03.046. View

3.
Russell R, Drummond H, Nimmo E, Anderson N, Smith L, Wilson D . Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease. Inflamm Bowel Dis. 2005; 11(11):955-64. DOI: 10.1097/01.mib.0000183423.38037.f3. View

4.
Ahmad T, Armuzzi A, Bunce M, Mulcahy-Hawes K, Marshall S, Orchard T . The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology. 2002; 122(4):854-66. DOI: 10.1053/gast.2002.32413. View

5.
Louis E, Collard A, Oger A, Degroote E, Aboul Nasr El Yafi F, Belaiche J . Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease. Gut. 2001; 49(6):777-82. PMC: 1728556. DOI: 10.1136/gut.49.6.777. View