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Leiomyomatosis Peritonealis Disseminata in Association with Currarino Syndrome?

Overview
Journal BMC Cancer
Publisher Biomed Central
Specialty Oncology
Date 2006 May 12
PMID 16686944
Citations 4
Authors
Affiliations
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Abstract

Background: Leiomyomatosis peritonealis disseminata (LPD) is a rare disease in which multiple smooth muscle or smooth muscle-like nodules develop subperitoneally in any part of the abdominal cavity. No reports of multiple congenital malformations associated with LPD have been found in the English literature.

Case Presentation: A 27 year-old patient referred to our gynaecology unit for pelvic pain, amenorrhoea, stress incontinence, chronic constipation and recurrent intestinal and urinary infections. Multiple congenital malformations had previously been diagnosed. Most of these had required surgical treatment in her early life: anorectal malformation with rectovestibular fistula, ectopic right ureteral orifice, megadolichoureter and hemisacrum. An ultrasound scan and computed tomography performed in our department showed an irregular, polylobate, complex 20 cm mass originating from the right pelvis that reached the right hypochondrium and the epigastrium. The patient underwent laparotomy. The three largest abdominal-pelvic masses and multiple independent nodules within the peritoneum were progressively removed. The histological diagnosis was of LPD.

Conclusion: The case we report is distinctive in that a rare acquired disease, LPD, coexists with multiple congenital malformations recalling a particular subgroup of caudal regression syndrome: the Currarino syndrome.

Citing Articles

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Gonzalez-Diaz E, Cengotitabengoa B, Dominguez Carbajo A, Fernandez Fernandez C, Corona A Ann Coloproctol. 2021; 37(Suppl 1):S58-S62.

PMID: 34107598 PMC: 8359697. DOI: 10.3393/ac.2020.10.13.1.


Leiomyomatosis peritonealis disseminata in a Nigerian woman.

Dim C, Akogu S, Ezegwui H, Olusina D Niger Med J. 2013; 53(3):172-4.

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Young-onset peri-anorectal leiomyomatosis: report of a case.

Toshima M, Miura K, Ishida K, Mizoi T, Naitoh T, Ogawa H Surg Today. 2012; 43(3):329-34.

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Leiomyomatosis Peritonealis Disseminata with Features of Carcinomatosis on Laparoscopy: A case report.

Al-Talib A, Al-Farsi A, Stanimir G Sultan Qaboos Univ Med J. 2011; 9(3):315-8.

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