» Articles » PMID: 16686587

Importance of Early Diagnosis and Treatment of Osteoporosis to Prevent Fractures

Overview
Journal Am J Manag Care
Specialty Health Services
Date 2006 May 12
PMID 16686587
Citations 16
Authors
Affiliations
Soon will be listed here.
Abstract

Osteoporosis affects about 10 million individuals in the United States, a number that is expected to increase substantially in coming decades as the elderly population burgeons. The chief debilitating consequence of osteoporosis, fracture, will affect about half the women and a third of the men in their lifetime, posing a daunting challenge to managed healthcare systems in terms of delivering optimal care and restraining cost. By encouraging optimal postfracture follow-up care and identifying those members at higher risk for fracture and in need of prompt treatment, managed care organizations can enhance the cost-effective management of osteoporosis, dampening downstream costs. This manuscript reviews the pathophysiology of osteoporosis, examines issues related to the diagnosis of osteoporosis, especially the role of bone mineral density measurement, and focuses on the impact of various treatment options in reducing fracture risk. Early assessment and treatment emerge as medically prudent steps in reducing the risk for osteoporosis-related fracture.

Citing Articles

Urinary pentosidine as a potential biomarker of impaired bone health: a systematic review and meta-analysis.

Shirinezhad A, Azarboo A, Mafhoumi A, Islampanah M, Mohammadi S, Ghaseminejad-Raeini A J Diabetes Metab Disord. 2024; 24(1):6.

PMID: 39697860 PMC: 11649614. DOI: 10.1007/s40200-024-01515-2.


Integration analysis of lncRNA and mRNA expression data identifies DOCK4 as a potential biomarker for elderly osteoporosis.

Wu C, Wang C, Xiao B, Li S, Sheng Y, Wang Q BMC Med Genomics. 2024; 17(1):70.

PMID: 38443923 PMC: 10916189. DOI: 10.1186/s12920-024-01837-3.


Artificial Intelligence Applications for Osteoporosis Classification Using Computed Tomography.

Ong W, Liu R, Makmur A, Low X, Sng W, Tan J Bioengineering (Basel). 2023; 10(12).

PMID: 38135954 PMC: 10741220. DOI: 10.3390/bioengineering10121364.


The potential of Klebsiella and Escherichia-Shigella and amino acids metabolism to monitor patients with postmenopausal osteoporosis in northwest China.

Liang Z, Hao Y, Yang L, Yuan P, Kang W, Liang T BMC Microbiol. 2023; 23(1):199.

PMID: 37495941 PMC: 10373412. DOI: 10.1186/s12866-023-02927-5.


Effect of adipokine and ghrelin levels on BMD and fracture risk: an updated systematic review and meta-analysis.

Lee S, Kim J, Jeon Y, Lee J, Kim K, Hwang S Front Endocrinol (Lausanne). 2023; 14:1044039.

PMID: 37181034 PMC: 10171108. DOI: 10.3389/fendo.2023.1044039.