The Systemic Inflammatory Response Syndrome

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2006 May 9

PMID 16679040

Citations 53

Authors

Charles M Robertson

Craig M Coopersmith

Affiliations

Soon will be listed here.

Abstract

The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic intervention in patients with this complex entity.

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