PCR Amplification of the IS6110 Insertion Element of Mycobacterium Tuberculosis in Fecal Samples from Patients with Intestinal Tuberculosis

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2006 May 5

PMID 16672431

Citations 28

Authors

Ramadass Balamurugan

Subramanian Venkataraman

K R John

Balakrishnan S Ramakrishna

Affiliations

Soon will be listed here.

Abstract

PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis in fecal samples was evaluated in the diagnosis of intestinal tuberculosis (ITB). The numbers of samples that tested positive by PCR with SalI digestion were 16/18 untreated-ITB samples, 0/8 treated-ITB samples, 12/14 smear-positive pulmonary tuberculosis samples, and 0/30 control samples. The sensitivity, specificity, positive predictive value, and negative predictive value of fecal PCR were 88.8%, 100%, 100%, and 93.7%, respectively.

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