The Surgical Management of Familial Adenomatous Polyposis in Northern Ireland

Overview

Journal Ulster Med J

Specialty General Medicine

Date 1991 Oct 1

PMID 1664549

Citations 1

Authors

W J Campbell

S T Irwin

T G Parks

Affiliations

Soon will be listed here.

Abstract

Sixty-eight patients from 18 families have been identified as having familial adenomatous polyposis during the past 30 years in Northern Ireland (population 1.5 million). Six of the 18 probands (33%) had developed colonic carcinoma when first seen at mean age 34 years. Ten of the 44 patients identified by surgical screening (21%) at a significantly lower mean age of 23 years had colonic carcinoma. Surgical management has generally been by subtotal colectomy with ileorectal anastomosis, or by panproctocolectomy and ileostomy.

Citing Articles

Results of national registration of familial adenomatous polyposis.

Bulow S Gut. 2003; 52(5):742-6.

PMID: 12692062 PMC: 1773626. DOI: 10.1136/gut.52.5.742.

References

HUBBARD Jr T . Familial polyposis of the colon: the fate of the retained rectum after colectomy in children. Am Surg. 1957; 23(6):577-86. View

MOERTEL C, Hill J, ADSON M . Surgical management of multiple polyposis. The problem of cancer in the retained bowel segment. Arch Surg. 1970; 100(4):521-6. DOI: 10.1001/archsurg.1970.01340220197033. View

Bussey H . The familial polyposis coli register. Ann Acad Med Singap. 1987; 16(3):532-4. View

Welling D, Beart Jr R . Surgical alternatives in the treatment of polyposis coli. Semin Surg Oncol. 1987; 3(2):99-104. DOI: 10.1002/ssu.2980030210. View

Pezim M, Pemberton J, Dozois R . Enteric continence and the ileal pouch-anal procedure. Semin Surg Oncol. 1987; 3(2):92-8. DOI: 10.1002/ssu.2980030209. View

Bussey H . Historical developments in familial polyposis coli. Semin Surg Oncol. 1987; 3(2):67-70. DOI: 10.1002/ssu.2980030204. View

Bulow S . Clinical features in familial polyposis coli. Results of the Danish Polyposis Register. Dis Colon Rectum. 1986; 29(2):102-7. DOI: 10.1007/BF02555389. View

Beart Jr R . Familial polyposis. Br J Surg. 1985; 72 Suppl:S31-2. DOI: 10.1002/bjs.1800721319. View

Bussey H, Eyers A, Ritchie S, Thomson J . The rectum in adenomatous polyposis: the St. Mark's policy. Br J Surg. 1985; 72 Suppl:S29-31. DOI: 10.1002/bjs.1800721318. View

10.

MORSON B, Bussey H . Magnitude of risk for cancer in patients with colorectal adenomas. Br J Surg. 1985; 72 Suppl:S23-5. DOI: 10.1002/bjs.1800721315. View

11.

Bulow S, Lauritsen K, Johansen A, Svendsen L, Sondergaard J . Gastroduodenal polyps in familial polyposis coli. Dis Colon Rectum. 1985; 28(2):90-3. DOI: 10.1007/BF02552651. View

12.

Fielding L, Stewart-Brown S, Blesovsky L, Kearney G . Anastomotic integrity after operations for large-bowel cancer: a multicentre study. Br Med J. 1980; 281(6237):411-4. PMC: 1713296. DOI: 10.1136/bmj.281.6237.411. View

13.

Harvey J, Quan S, Stearns M . Management of familial polyposis with preservation of the rectum. Surgery. 1978; 84(4):476-82. View

14.

DECOSSE J, Adams M, Condon R . Familial polyposis. Cancer. 1977; 39(1):267-73. DOI: 10.1002/1097-0142(197701)39:1<267::aid-cncr2820390141>3.0.co;2-x. View

15.

Kmiot W, Williams M, Keighley M . Pouchitis following colectomy and ileal reservoir construction for familial adenomatous polyposis. Br J Surg. 1990; 77(11):1283. DOI: 10.1002/bjs.1800771128. View