Twin Gestation Pregnancies: Genetic Counseling and Testing Experience

Overview

Journal J Genet Couns

Publisher Wiley

Specialty Genetics

Date 2006 Apr 28

PMID 16642275

Citations 3

Authors

Kathryn F Peters

Brian M Saltsman

Stephen A Petrill

Affiliations

Soon will be listed here.

Abstract

We report on the prenatal genetic counseling and testing experience in 343 pregnancies with twin or higher multiple gestations. By self-report, 8% (27/343) parents of these pregnancies reported meeting with a genetic counselor, and 23% (79/343) elected prenatal genetic testing. The most common testing procedures elected were maternal serum analyte screening and amniocentesis to identify fetuses with aneuploidy or neural tube defects. Use of prenatal genetic testing was correlated with advanced maternal age. No association was found between use of genetic testing and use of OI/ART or the length of time needed to conceive. Forty percent (11/27) of those who met with a genetic counselor opted to decline prenatal testing/screening. These data suggest that although clients with multiple gestation pregnancies would likely benefit from genetic counseling, many are not availing themselves of this service. Implications of these data for the genetic counseling profession are discussed.

Citing Articles

Attitude changes toward prenatal testing among women with twin pregnancies after the introduction of noninvasive prenatal testing: A single-center study in Japan.

Ogawa M, Hasuo Y, Taura Y, Tsunematsu R, Shikada S, Matsushita Y J Obstet Gynaecol Res. 2021; 47(11):3813-3820.

PMID: 34490692 PMC: 9292293. DOI: 10.1111/jog.15010.

Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies.

Reese K, Czerwinski J, Darilek S, Johnson A, Jones M, Singletary C J Genet Couns. 2018; 27(5):1238-1247.

PMID: 29525932 DOI: 10.1007/s10897-018-0246-4.

Screening and Invasive Testing in Twins.

Monni G, Iuculano A, Zoppi M J Clin Med. 2015; 3(3):865-82.

PMID: 26237482 PMC: 4449657. DOI: 10.3390/jcm3030865.

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