Cervical Neoplasia and Human Papilloma Virus Infection in Prostitutes

Overview

Journal Genitourin Med

Specialty Infectious Diseases

Date 1991 Dec 1

PMID 1663486

Citations 6

Authors

G Gitsch

C Kainz

A Reinthaller

W Kopp

G TATRA

G Breitenecker

Affiliations

Soon will be listed here.

Abstract

Objectives: To evaluate the prevalence and incidence of PAP smears indicating cervical dysplasia as well as human papillomavirus (HPV) infection in prostitutes.

Design: Prevalence and incidence study of cervical dysplasia and HPV infection in prostitutes. For detection and typing of HPV-DNA In Situ Hybridisation (ISH) was performed in tissue samples with CIN gained by colposcopically directed punch biopsies.

Setting: Second Department of Obstetrics and Gynecology, University of Vienna Medical School and STD Clinic of the Public Health Office, Vienna.

Subjects: Registered prostitutes attending the STD Clinic of the Public Health Office and a control group.

Results: 978 prostitutes and 5493 women with unknown cytological anamnesis were compared. Frequency of positive PAP smears was significantly higher in prostitutes (6.13% versus 1.43%). To determine the pick-up rate of cervical dysplasia during one year after negative cytology we compared 722 prostitutes and 3162 controls. Prostitutes showed a significant higher dysplasia pick-up rate (3.05% to 1.07%) compared with controls. HPV detection rate in prostitutes was similar to that in the control group. The distribution of HPV types revealed a higher frequency of "high risk" HPV 16/18 and 31/33 in prostitutes.

Conclusion: The results demonstrate a higher incidence and prevalence of cervical dysplasia in prostitutes and therefore suggest regular cervical PAP smear screening in registered prostitutes twice a year.

Citing Articles

Knowledge, Attitude and Practice of Commercial Sex Workers Regarding Cervical Cancer and Its Screening, Daulatdia Brothel, Rajbari District, Bangladesh, 2020-2021.

Qayum M, Hassan M, Henderson A, Billah M, Nurunnahar M, Afser S Asian Pac J Cancer Prev. 2022; 23(12):4085-4092.

PMID: 36579989 PMC: 9971462. DOI: 10.31557/APJCP.2022.23.12.4085.

In silico design of a multi-epitope vaccine against HPV16/18.

Sanami S, Rafieian-Kopaei M, Ashrafi Dehkordi K, Pazoki-Toroudi H, Azadegan-Dehkordi F, Mobini G BMC Bioinformatics. 2022; 23(1):311.

PMID: 35918631 PMC: 9344258. DOI: 10.1186/s12859-022-04784-x.

Molecular genotyping of human papillomavirus l1 gene in low-risk and high-risk populations in Bangkok.

Leaungwutiwong P, Bamrungsak B, Jittmittraphap A, Maneekan P, Kosoltanapiwat N, Kalambaheti T Sex Transm Dis. 2015; 42(4):208-17.

PMID: 25763674 PMC: 4358745. DOI: 10.1097/OLQ.0000000000000259.

Systematic review of facility-based sexual and reproductive health services for female sex workers in Africa.

Dhana A, Luchters S, Moore L, Lafort Y, Roy A, Scorgie F Global Health. 2014; 10:46.

PMID: 24916010 PMC: 4070634. DOI: 10.1186/1744-8603-10-46.

HPV vaccination programs have not been shown to be cost-effective in countries with comprehensive Pap screening and surgery.

Wilyman J Infect Agent Cancer. 2013; 8(1):21.

PMID: 23758803 PMC: 3698073. DOI: 10.1186/1750-9378-8-21.

References

PEREYRA A . The relationship of sexual activity to cervical cancer. Cancer of the cervix in a prison population. Obstet Gynecol. 1961; 17:154-9. View

Naguib S, LUNDIN Jr F, Davis H . Relation of various epidemiologic factors to cervical cancer as determined by a screening program. Obstet Gynecol. 1966; 28(4):451-9. View

Syrjanen K, de Villiers E, Saarikoski S, CASTREN O, VAYRYNEN M, Mantyjarvi R . Cervical papillomavirus infection progressing to invasive cancer in less than three years. Lancet. 1985; 1(8427):510-1. DOI: 10.1016/s0140-6736(85)92102-6. View

Meanwell C, Cox M, Blackledge G, Maitland N . HPV 16 DNA in normal and malignant cervical epithelium: implications for the aetiology and behaviour of cervical neoplasia. Lancet. 1987; 1(8535):703-7. DOI: 10.1016/s0140-6736(87)90353-9. View

Fuchs P, Girardi F, Pfister H . Human papillomavirus DNA in normal, metaplastic, preneoplastic and neoplastic epithelia of the cervix uteri. Int J Cancer. 1988; 41(1):41-5. DOI: 10.1002/ijc.2910410109. View

Reid R, Greenberg M, Jenson A, Husain M, Willett J, Daoud Y . Sexually transmitted papillomaviral infections. I. The anatomic distribution and pathologic grade of neoplastic lesions associated with different viral types. Am J Obstet Gynecol. 1987; 156(1):212-22. DOI: 10.1016/0002-9378(87)90241-9. View

Syrjanen K, Mantyjarvi R, VAYRYNEN M, Syrjanen S, Parkkinen S, Yliskoski M . Human papillomavirus (HPV) infections involved in the neoplastic process of the uterine cervix as established by prospective follow-up of 513 women for two years. Eur J Gynaecol Oncol. 1987; 8(1):5-16. View

REEVES W, Arosemena J, Garcia M, De Lao S, Cuevas M, Quiroz E . Genital human papillomavirus infection in Panama City prostitutes. J Infect Dis. 1989; 160(4):599-603. DOI: 10.1093/infdis/160.4.599. View

Abeyewickreme I . Cervical cytology screening in a sexually transmitted diseases clinic for the first time in Sri Lanka. Genitourin Med. 1989; 65(2):98-102. PMC: 1194296. DOI: 10.1136/sti.65.2.98. View

10.

Goppinger A, Birmelin G, Hauser U, Ikenberg H . [Clinical aspects of HPV-16/18 associated cervical lesions]. Geburtshilfe Frauenheilkd. 1990; 50(2):106-9. DOI: 10.1055/s-2007-1026444. View

11.

Reid R, Stanhope C, Herschman B, Booth E, Phibbs G, Smith J . Genital warts and cervical cancer. I. Evidence of an association between subclinical papillomavirus infection and cervical malignancy. Cancer. 1982; 50(2):377-87. DOI: 10.1002/1097-0142(19820715)50:2<377::aid-cncr2820500236>3.0.co;2-a. View

12.

Sebastian J, Leeb B, See R . Cancer of the cervix--a sexually transmitted disease. Cytologic screening in a prostitute population. Am J Obstet Gynecol. 1978; 131(6):620-3. DOI: 10.1016/0002-9378(78)90819-0. View

13.

MOGHISSI K, MACK H . Epidemiology of cervical cancer: study of a prison population. Am J Obstet Gynecol. 1968; 100(5):607-14. DOI: 10.1016/s0002-9378(15)33386-x. View

14.

KEIGHLEY E . Carcinoma of the cervix among prostitutes in a women's prison. Br J Vener Dis. 1968; 44(3):254-5. PMC: 1047962. DOI: 10.1136/sti.44.3.254. View

15.

zur Hausen H . Intracellular surveillance of persisting viral infections. Human genital cancer results from deficient cellular control of papillomavirus gene expression. Lancet. 1986; 2(8505):489-91. DOI: 10.1016/s0140-6736(86)90360-0. View