Medullary Sponge Kidney Associated with Distal Renal Tubular Acidosis in a 5-year-old Girl

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2006 Apr 8

PMID 16602004

Citations 4

Authors

Belde Kasap

Alper Soylu

Oguz Oren

Mehmet Turkmen

Salih Kavukcu

Affiliations

Soon will be listed here.

Abstract

Introduction: Medullary sponge kidney (MSK) is characterized by cystic dilatation of the inner medullary collecting ducts, which causes the kidneys to resemble a sponge.

Case Report: Although distal renal tubular acidosis (dRTA) is commonly observed in patients with MSK, we report a 5-year-old girl with MSK who had features of both dRTA (nephrocalcinosis, hypercalciuria, hypocitraturia) and proximal tubular dysfunction (hyperuricosuria, impaired tubular phosphate reabsorption and proteinuria).

Discussion: Metabolic acidosis, hypercalciuria, hypocitraturia, tubular phosphate reabsorption and growth retardation in the patient improved with alkali therapy.

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Bone disease in medullary sponge kidney and effect of potassium citrate treatment.

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