A Bacterium That Has Three Pathways to Regulate Membrane Lipid Fluidity

Overview

Journal Mol Microbiol

Specialties Microbiology
Molecular Biology

Date 2006 Apr 1

PMID 16573678

Citations 8

Authors

John E Cronan

Affiliations

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Abstract

Well-studied bacteria such as Bacillus subtilis and Escherichia coli each have only a single pathway for synthesis of the unsaturated fatty acids required to make functional membrane lipids. In marked contrast, unsaturated fatty acid synthesis in Pseudomonas aeruginosa proceeds by three distinct pathways.

Citing Articles

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Transcription factors FabR and FadR regulate both aerobic and anaerobic pathways for unsaturated fatty acid biosynthesis in Shewanella oneidensis.

Luo Q, Shi M, Ren Y, Gao H Front Microbiol. 2015; 5:736.

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A novel role for an ECF sigma factor in fatty acid biosynthesis and membrane fluidity in Pseudomonas aeruginosa.

Boechat A, Kaihami G, Politi M, Lepine F, Baldini R PLoS One. 2014; 8(12):e84775.

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