MyoD1 Protein Expression in Alveolar Soft Part Sarcoma As Confirmatory Evidence of Its Skeletal Muscle Nature

Overview

Journal Am J Surg Pathol

Date 1991 Oct 1

PMID 1656801

Citations 18

Authors

J Rosai

P Dias

D M Parham

D N Shapiro

P Houghton

Affiliations

Soon will be listed here.

Abstract

A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.

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