Type III Secretion Gets an LcrV Tip

Overview

Journal Trends Microbiol

Date 2006 Mar 28

PMID 16564172

Citations 17

Authors

Luis Jaime Mota

Affiliations

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Abstract

Type III secretion is used by many Gram-negative pathogenic bacteria to inject effector proteins into eukaryotic host cells. Effector delivery requires a secretion apparatus, called an injectisome or needle complex, and the assembly of a translocation pore in a target-cell membrane. Recent work provides evidence that enlightens the view of how pore assembly might occur and of how the injectisome and the pore might be linked.

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