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Antibody Formation in Rabbits Adapted and Nonadapted to High Altitude

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Journal Infect Immun
Date 1971 Feb 1
PMID 16557978
Citations 1
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Abstract

Antibody formation in high-altitude-acclimatized and nonacclimatized rabbits was investigated at altitudes of 14,100 (Pikes Peak, Colo.) and 5,330 (Denver, Colo.). Serum pools representing samplings of primary response were titered before and after treatment with 2-mercaptoethanol. Peak titers of 2-mercaptoethanolresistant and -sensitive humoral antibodies were higher in the animals adapted to an altitude of 14,100 ft and in nonadapted animals than in animals maintained at 5,330 ft.

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