Retention and Removal of a New Viscous Dispersive Ophthalmic Viscosurgical Device During Cataract Surgery in Animal Eyes

Overview

Journal Br J Ophthalmol

Specialty Ophthalmology

Date 2006 Mar 21

PMID 16547332

Citations 18

Authors

T Oshika

F Okamoto

Y Kaji

T Hiraoka

T Kiuchi

M Sato

K Kawana

Affiliations

Soon will be listed here.

Abstract

Aims: To assess the retention and removal properties of a new viscous dispersive ophthalmic viscosurgical device (OVD), DisCoVisc, in comparison with those of cohesive (Provisc), dispersive (Viscoat), and viscoadaptive (Healon5) OVDs.

Methods: In 20 porcine eyes, cataract surgery was simulated using one of the four OVDs which were stained with fluorescein for better visualisation. Three parameters were measured. Firstly, the presence/absence of OVDs in the chamber at the completion of phacoemulsification was recorded. Secondly, the time until the OVDs were completely removed from the anterior chamber using the phaco needle was measured. Thirdly, after intraocular lens (IOL) implantation, the time needed to completely remove the OVDs from the chamber with irrigation/aspiration tip was recorded.

Results: At the completion of phacoemulsification, the OVDs retained in 0% (0/5) for Provisc, 80% (4/5) for Healon5, 100% (5/5) for DisCoVisc, and 100% (5/5) for Viscoat. The retention of OVDs during phacoemulsification was greatest with Viscoat followed by, in descending order, DisCoVisc, Healon5, and Provisc. The removal of OVDs after IOL implantation took longest with Viscoat followed by Healon5, DisCoVisc, and Provisc.

Conclusion: The viscous dispersive DisCoVisc showed excellent retention during phacoemulsification, while its removal after IOL implantation was very easy. When compared with the viscoadaptive Healon5, DisCoVisc was retained better in the chamber and was easier to remove. These features of DisCoVisc should be highly advantageous when considering covering the entire cataract surgery procedure with a single OVD.

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References

Assia E, Apple D, Lim E, Morgan R, Tsai J . Removal of viscoelastic materials after experimental cataract surgery in vitro. J Cataract Refract Surg. 1992; 18(1):3-6. DOI: 10.1016/s0886-3350(13)80376-8. View

Poyer J, Chan K, Arshinoff S . New method to measure the retention of viscoelastic agents on a rabbit corneal endothelial cell line after irrigation and aspiration. J Cataract Refract Surg. 1998; 24(1):84-90. DOI: 10.1016/s0886-3350(98)80079-5. View

McDermott M, Hazlett L, Barrett R, Lambert R . Viscoelastic adherence to corneal endothelium following phacoemulsification. J Cataract Refract Surg. 1998; 24(5):678-83. DOI: 10.1016/s0886-3350(98)80265-4. View

Arshinoff S . Dispersive-cohesive viscoelastic soft shell technique. J Cataract Refract Surg. 1999; 25(2):167-73. DOI: 10.1016/s0886-3350(99)80121-7. View

Auffarth G, Holzer M, Visessook N, Apple D, Volcker H . Removal times for a dispersive and a cohesive ophthalmic viscosurgical device correlated with intraocular lens material. J Cataract Refract Surg. 2004; 30(11):2410-4. DOI: 10.1016/j.jcrs.2004.03.039. View

Tetz M, Holzer M . Two-compartment technique to remove ophthalmic viscosurgical devices. J Cataract Refract Surg. 2000; 26(5):641-3. DOI: 10.1016/s0886-3350(99)00420-4. View

Auffarth G, Holzer M, Vissesook N, Apple D, Volcker H . Removal times and techniques of a viscoadaptive ophthalmic viscosurgical device. J Cataract Refract Surg. 2004; 30(4):879-83. DOI: 10.1016/j.jcrs.2003.08.031. View

Dick H, Krummenauer F, Augustin A, Pakula T, Pfeiffer N . Healon5 viscoadaptive formulation: Comparison to Healon and Healon GV. J Cataract Refract Surg. 2001; 27(2):320-6. DOI: 10.1016/s0886-3350(00)00482-x. View

Tetz M, Holzer M, Lundberg K, Auffarth G, Burk R, Kruse F . Clinical results of phacoemulsification with the use of Healon5 or Viscoat. J Cataract Refract Surg. 2001; 27(3):416-20. DOI: 10.1016/s0886-3350(00)00569-1. View

10.

Zetterstrom C, Wejde G, Taube M . Healon5: comparison of 2 removal techniques. J Cataract Refract Surg. 2002; 28(9):1561-4. DOI: 10.1016/s0886-3350(02)01271-3. View

11.

Arshinoff S, Wong E . Understanding, retaining, and removing dispersive and pseudodispersive ophthalmic viscosurgical devices. J Cataract Refract Surg. 2004; 29(12):2318-23. DOI: 10.1016/j.jcrs.2003.09.045. View

12.

Oshika T, Eguchi S, Oki K, Yaguchi S, Bissen-Miyajima H, Ota I . Clinical comparison of Healon5 and Healon in phacoemulsification and intraocular lens implantation; Randomized multicenter study. J Cataract Refract Surg. 2004; 30(2):357-62. DOI: 10.1016/S0886-3350(03)00615-1. View

13.

Schwenn O, Dick H, Krummenauer F, Christmann S, Vogel A, Pfeiffer N . Healon5 versus Viscoat during cataract surgery: intraocular pressure, laser flare and corneal changes. Graefes Arch Clin Exp Ophthalmol. 2000; 238(10):861-7. DOI: 10.1007/s004170000192. View