Inhibitory Effects of Secondary Metabolites from the Red Alga Delisea Pulchra on Swarming Motility of Proteus Mirabilis

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 1996 Nov 1

PMID 16535454

Citations 37

Authors

L Gram

R de Nys

R Maximilien

M Givskov

P Steinberg

S Kjelleberg

Affiliations

Soon will be listed here.

Abstract

Abnormal, uncoordinated swarming motility of the opportunistic human pathogen Proteus mirabilis was seen when a crude extract of the Australian red alga Delisea pulchra was added to the medium. This occurred at concentrations at which growth rate, swimming motility, cell elongation, polynucleation, and hyperflagellation were not affected. One halogenated furanone from D. pulchra inhibited swarming motility at concentrations that did not affect growth rate and swimming motility. Other structurally similar D. pulchra furanones had no effect on swarming, suggesting considerable specificity in the effects of furanones on swarming motility by P. mirabilis.

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