Time-resolved 3D Contrast-enhanced MRA with GRAPPA on a 1.5-T System for Imaging of Craniocervical Vascular Disease: Initial Experience

Overview

Journal Neuroradiology

Specialties Neurology
Radiology

Date 2006 Mar 15

PMID 16532336

Citations 16

Authors

Stephan Meckel

Ralf Mekle

Christian Taschner

Sven Haller

Klaus Scheffler

Ernst-Wilhelm Radue

Stephan G Wetzel

Affiliations

Soon will be listed here.

Abstract

Introduction: For three-dimensional (3D) imaging with magnetic resonance angiography (MRA) of the cerebral and cervical circulation, both a high temporal and a high spatial resolution with isovolumetric datasets are of interest. In an initial evaluation, we analyzed the potential of contrast-enhanced (CE) time-resolved 3D-MRA as an adjunct for neurovascular MR imaging.

Methods: In ten patients with various cerebrovascular disorders and vascularized tumors in the cervical circulation, high-speed MR acquisition using parallel imaging with the GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) algorithm on a 1.5-T system with a temporal resolution of 1.5 s per dataset and a nearly isovolumetric spatial resolution was applied. The results were assessed and compared with those from conventional MRA and digital subtraction angiography (DSA).

Results: CE time-resolved 3D-MRA enabled the visualization and characterization of high-flow arteriovenous shunts in cases of vascular malformations or hypervascularized tumors. In steno-occlusive disease, the method provided valuable additional information about altered vessel perfusion compared to standard MRA techniques such as time-of-flight (TOF) MRA. The use of a nearly isovolumetric voxel size allowed a free-form interrogation of 3D datasets. Its comparatively low spatial resolution was found to be the major limitation.

Conclusion: In this preliminary analysis, CE time-resolved 3D-MRA was revealed to be a promising complementary MRA sequence that enabled the visualization of contrast flow dynamics in various types of neurovascular disorders and vascularized cervical tumors.

Citing Articles

Recent advances in 3D time-resolved contrast-enhanced MR angiography.

Riederer S, Haider C, Borisch E, Weavers P, Young P J Magn Reson Imaging. 2015; 42(1):3-22.

PMID: 26032598 PMC: 4478169. DOI: 10.1002/jmri.24880.

Vascular masking for improved unfolding in 2D SENSE-accelerated 3D contrast-enhanced MR angiography.

Stinson E, Borisch E, Johnson C, Trzasko J, Young P, Riederer S J Magn Reson Imaging. 2013; 39(5):1161-70.

PMID: 23897776 PMC: 3818335. DOI: 10.1002/jmri.24266.

Acceleration apportionment: a method of improved 2D SENSE acceleration applied to 3D contrast-enhanced MR angiography.

Weavers P, Borisch E, Johnson C, Riederer S Magn Reson Med. 2013; 71(2):672-80.

PMID: 23450817 PMC: 3735825. DOI: 10.1002/mrm.24700.

Time-resolved MR angiography of the intracranial venous system: an alternative MR venography technique.

Yigit H, Turan A, Ergun E, Kosar P, Kosar U Eur Radiol. 2011; 22(5):980-9.

PMID: 22101744 DOI: 10.1007/s00330-011-2330-0.

Time-resolved 3D contrast-enhanced MRA on 3.0T: a non-invasive follow-up technique after stent-assisted coil embolization of the intracranial aneurysm.

Choi J, Roh H, Moon W, Kim N, Moon S, Kang C Korean J Radiol. 2011; 12(6):662-70.

PMID: 22043147 PMC: 3194769. DOI: 10.3348/kjr.2011.12.6.662.

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