Effect of Protease Inhibitors on Focus Formation by Murine Sarcoma Virus

Overview

Journal J Natl Cancer Inst

Publisher Oxford University Press

Specialty Oncology

Date 1975 May 1

PMID 165316

Citations 2

Authors

Y Yuasa

H Shimojo

T Aoyagi

H Umezawa

Affiliations

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Abstract

The effect of six protease inhibitors, isolated from various species of actinomycetes, on focus formation by murine sarcoma virus was examined. Pepstatin was the only inhibitor. The treatment of cells with pepstatin at various times possibly retards the early stage of infection with murine sarcoma virus.

Citing Articles

Role of protease in mouse hepatitis virus-induced cell fusion. Studies with a cold-sensitive mutant isolated from a persistent infection.

Yoshikura H, TEJIMA S Virology. 1981; 113(2):503-11.

PMID: 6267795 PMC: 7130590. DOI: 10.1016/0042-6822(81)90178-1.

Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A.

Seelmeier S, Schmidt H, Turk V, von der Helm K Proc Natl Acad Sci U S A. 1988; 85(18):6612-6.

PMID: 3045820 PMC: 282027. DOI: 10.1073/pnas.85.18.6612.