Predictors of Antisocial Behaviour in Children with Attention Deficit Hyperactivity Disorder

Overview

Journal Eur Child Adolesc Psychiatry

Specialties Pediatrics
Psychiatry

Date 2006 Mar 9

PMID 16523253

Citations 21

Authors

Anita Thapar

Marianne van den Bree

Tom Fowler

Kate Langley

Naureen Whittinger

Affiliations

Soon will be listed here.

Abstract

Introduction: Antisocial behaviour is an important adverse outcome of ADHD. The aim of this review is to examine what is known about the clinical, genetic and environmental factors that contribute to the link between ADHD and antisocial behaviour.

Methods: Electronic literature searches for the years 1980-2004 and examination of key reference books were undertaken.

Results: ADHD symptom severity and pervasiveness predict the development of antisocial behaviour. Genetic factors contribute substantially to the risk of developing both problems, although specific genes that influence the development of antisocial behaviour in ADHD have yet to be identified. Some of these genetic effects may be indirectly mediated through environmental risk (gene-environment correlation) or by increasing individual susceptibility to specific environmental adversity (gene-environment interaction). Antisocial behaviour in children with ADHD is also linked with family adversity as well as peer rejection, although some of this adversity may arise as a result of the child's symptoms.

Conclusion: Despite the increased risk of antisocial outcomes in those with ADHD, relatively little is known about what risk factors and mechanisms contribute to the link between both these problems. Given the need for appropriate intervention and prevention strategies and targeting resources, more research is needed in this area.

Citing Articles

The impacts associated with having ADHD: an umbrella review.

French B, Nalbant G, Wright H, Sayal K, Daley D, Groom M Front Psychiatry. 2024; 15:1343314.

PMID: 38840946 PMC: 11151783. DOI: 10.3389/fpsyt.2024.1343314.

Oroxylin A: A Promising Flavonoid for Prevention and Treatment of Chronic Diseases.

Sajeev A, Hegde M, Girisa S, Devanarayanan T, AlQahtani M, Abbas M Biomolecules. 2022; 12(9).

PMID: 36139025 PMC: 9496116. DOI: 10.3390/biom12091185.

Risk and resource factors of antisocial behaviour in children and adolescents: results of the longitudinal BELLA study.

Otto C, Kaman A, Erhart M, Barkmann C, Klasen F, Schlack R Child Adolesc Psychiatry Ment Health. 2021; 15(1):61.

PMID: 34686200 PMC: 8539834. DOI: 10.1186/s13034-021-00412-3.

Attachment Anxiety Moderates the Association Between ADHD and Psychological Distress.

Kordahji H, Ben-David S, Elkana O Psychiatr Q. 2021; 92(4):1711-1724.

PMID: 34245401 DOI: 10.1007/s11126-021-09919-6.

Association Between Childhood Behaviors and Adult Employment Earnings in Canada.

Vergunst F, Tremblay R, Nagin D, Algan Y, Beasley E, Park J JAMA Psychiatry. 2019; 76(10):1044-1051.

PMID: 31215972 PMC: 6584893. DOI: 10.1001/jamapsychiatry.2019.1326.

References

Tillman R, Geller B, Craney J, Bolhofner K, Williams M, Zimerman B . Temperament and character factors in a prepubertal and early adolescent bipolar disorder phenotype compared to attention deficit hyperactive and normal controls. J Child Adolesc Psychopharmacol. 2004; 13(4):531-43. DOI: 10.1089/104454603322724922. View

Mannuzza S, Klein R, Bessler A, Malloy P, LaPadula M . Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. Arch Gen Psychiatry. 1993; 50(7):565-76. DOI: 10.1001/archpsyc.1993.01820190067007. View

Linnet K, Dalsgaard S, Obel C, Wisborg K, Henriksen T, Rodriguez A . Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence. Am J Psychiatry. 2003; 160(6):1028-40. DOI: 10.1176/appi.ajp.160.6.1028. View

Rosler M, Retz W, Retz-Junginger P, Hengesch G, Schneider M, Supprian T . Prevalence of attention deficit-/hyperactivity disorder (ADHD) and comorbid disorders in young male prison inmates. Eur Arch Psychiatry Clin Neurosci. 2004; 254(6):365-71. DOI: 10.1007/s00406-004-0516-z. View

Fergusson D, Horwood L, Ridder E . Show me the child at seven II: Childhood intelligence and later outcomes in adolescence and young adulthood. J Child Psychol Psychiatry. 2005; 46(8):850-8. DOI: 10.1111/j.1469-7610.2005.01472.x. View

Kotimaa A, Moilanen I, Taanila A, Ebeling H, Smalley S, McGough J . Maternal smoking and hyperactivity in 8-year-old children. J Am Acad Child Adolesc Psychiatry. 2003; 42(7):826-33. DOI: 10.1097/01.CHI.0000046866.56865.A2. View

Hirshfeld-Becker D, Biederman J, Faraone S, Violette H, Wrightsman J, Rosenbaum J . Temperamental correlates of disruptive behavior disorders in young children: preliminary findings. Biol Psychiatry. 2002; 51(7):563-74. DOI: 10.1016/s0006-3223(01)01299-9. View

Beitchman J, Davidge K, Kennedy J, Atkinson L, Lee V, Shapiro S . The serotonin transporter gene in aggressive children with and without ADHD and nonaggressive matched controls. Ann N Y Acad Sci. 2004; 1008:248-51. DOI: 10.1196/annals.1301.025. View

Curran S, Fitzgerald M . Attention deficit hyperactivity disorder in the prison population. Am J Psychiatry. 1999; 156(10):1664-5. DOI: 10.1176/ajp.156.10.1664-a. View

10.

Van den Bergh B, Marcoen A . High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8- and 9-year-olds. Child Dev. 2004; 75(4):1085-97. DOI: 10.1111/j.1467-8624.2004.00727.x. View

11.

Thapar A, Holmes J, Poulton K, Harrington R . Genetic basis of attention deficit and hyperactivity. Br J Psychiatry. 1999; 174:105-11. DOI: 10.1192/bjp.174.2.105. View

12.

Jensen P, Martin D, Cantwell D . Comorbidity in ADHD: implications for research, practice, and DSM-V. J Am Acad Child Adolesc Psychiatry. 1997; 36(8):1065-79. DOI: 10.1097/00004583-199708000-00014. View

13.

Rutter M, Silberg J . Gene-environment interplay in relation to emotional and behavioral disturbance. Annu Rev Psychol. 2001; 53:463-90. DOI: 10.1146/annurev.psych.53.100901.135223. View

14.

Loeber R, Stouthamer-Loeber M, White H . Developmental aspects of delinquency and internalizing problems and their association with persistent juvenile substance use between ages 7 and 18. J Clin Child Psychol. 1999; 28(3):322-32. DOI: 10.1207/S15374424jccp280304. View

15.

Miller-Johnson S, Coie J, Bierman K . Peer rejection and aggression and early starter models of conduct disorder. J Abnorm Child Psychol. 2002; 30(3):217-30. PMC: 2774087. DOI: 10.1023/a:1015198612049. View

16.

Burt S, Krueger R, McGue M, Iacono W . Parent-child conflict and the comorbidity among childhood externalizing disorders. Arch Gen Psychiatry. 2003; 60(5):505-13. DOI: 10.1001/archpsyc.60.5.505. View

17.

Disney E, Elkins I, McGue M, Iacono W . Effects of ADHD, conduct disorder, and gender on substance use and abuse in adolescence. Am J Psychiatry. 1999; 156(10):1515-21. DOI: 10.1176/ajp.156.10.1515. View

18.

Gresham F, Macmillan D, Bocian K, Ward S, Forness S . Comorbidity of hyperactivity-impulsivity-inattention and conduct problems: risk factors in social, affective, and academic domains. J Abnorm Child Psychol. 1998; 26(5):393-406. DOI: 10.1023/a:1021908024028. View

19.

Bobb A, Castellanos F, Addington A, Rapoport J . Molecular genetic studies of ADHD: 1991 to 2004. Am J Med Genet B Neuropsychiatr Genet. 2005; 132B(1):109-25. View

20.

Fergusson D, Horwood L . Predictive validity of categorically and dimensionally scored measures of disruptive childhood behaviors. J Am Acad Child Adolesc Psychiatry. 1995; 34(4):477-85; discussion 485-7. View