Conversion of Sphingobium Chlorophenolicum ATCC 39723 to a Hexachlorobenzene Degrader by Metabolic Engineering

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 2006 Mar 7

PMID 16517689

Citations 12

Authors

Da-Zhong Yan

Hong Liu

Ning-Yi Zhou

Affiliations

Soon will be listed here.

Abstract

The gene cassette (camA+ camB+ camC) encoding a cytochrome P-450cam variant was integrated into the nonessential gene pcpM of the pentachlorophenol degrader Sphingobium chlorophenolicum ATCC 39723 by homologous recombination. The recombinant strain could degrade hexachlorobenzene at a rate of 0.67 nmol.mg (dry weight)-1.h-1, and intermediate pentachlorophenol was also identified.

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