Virus Entry: Open Sesame

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2006 Feb 25

PMID 16497584

Citations 541

Authors

Mark Marsh

Ari Helenius

Affiliations

Soon will be listed here.

Abstract

Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells. These insights are revolutionizing our understanding of endocytosis and the movement of vesicles within cells. In addition, such insights reveal new targets for attacking viruses before they can usurp the host-cell machinery for replication.

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