[Microarrays for the Identification of Molecular Markers in the Diagnosis and Therapy of Renal Cell Carcinomas]

Overview

Journal Urologe A

Specialty Urology

Date 2006 Feb 9

PMID 16465525

Authors

H Sultmann

A Poustka

Affiliations

Soon will be listed here.

Abstract

Within the framework of the large interdisciplinary projects in biology, in particular the human genome project, a variety of novel technologies with unprecedented value for the analysis of clinical issues have been developed. DNA microarrays are a prominent example of this: they are powerful tools to investigate global gene expression in tumors and their corresponding normal tissues, to classify tumors based on their molecular properties, and to identify novel targets for future tumor therapy. Here, we review recent results of global gene expression analyses in renal cell carcinoma and discuss their implications for the diagnosis, prognosis, and therapy of human cancer.

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