Identification of a Gene Encoding a Functional Reverse Transcriptase Within a Highly Variable Locus in the P2-like Coliphages

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2006 Feb 3

PMID 16452449

Citations 19

Authors

Richard Odegrip

Anders S Nilsson

Elisabeth Haggard-Ljungquist

Affiliations

Soon will be listed here.

Abstract

The P2-like coliphages are highly similar; the structural genes show at least 96% identity. However, at two loci they have genes believed to be horizontally transferred. We show that the genetic content at the second loci, the TO region, contains six completely different sequences with high AT contents and with different open reading frames. The product of one of them exhibits reverse transcriptase activity and blocks infection of phage T5.

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