Genetic and Epigenetic Mechanisms in the Early Development of the Vascular System

Overview

Journal J Anat

Specialty Anatomy & Histology

Date 2006 Jan 31

PMID 16441559

Citations 14

Authors

Domenico Ribatti

Affiliations

Soon will be listed here.

Abstract

The cardiovascular system plays a critical role in vertebrate development and homeostasis. Vascular development is a highly organized sequence of events that requires the correct spatial and temporal expression of specific sets of genes leading to the development of a primary vascular network. There have been intensive efforts to determine the molecular mechanisms regulating vascular growth and development, and much of the rationale for this has stemmed from the increasing clinical importance and therapeutic potential of modulating vascular formation during various disease states.

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References

Neufeld G, Cohen T, Shraga N, Lange T, Kessler O, Herzog Y . The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc Med. 2002; 12(1):13-9. DOI: 10.1016/s1050-1738(01)00140-2. View

Brooks P, Clark R, Cheresh D . Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 1994; 264(5158):569-71. DOI: 10.1126/science.7512751. View

Wang H, Chen Z, Anderson D . Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998; 93(5):741-53. DOI: 10.1016/s0092-8674(00)81436-1. View

Eichmann A, Corbel C, Nataf V, Vaigot P, Breant C, Le Douarin N . Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2. Proc Natl Acad Sci U S A. 1997; 94(10):5141-6. PMC: 24645. DOI: 10.1073/pnas.94.10.5141. View

Davis S, Yancopoulos G . The angiopoietins: Yin and Yang in angiogenesis. Curr Top Microbiol Immunol. 1999; 237:173-85. DOI: 10.1007/978-3-642-59953-8_9. View

Kawasaki T, Kitsukawa T, Bekku Y, Matsuda Y, Sanbo M, Yagi T . A requirement for neuropilin-1 in embryonic vessel formation. Development. 1999; 126(21):4895-902. DOI: 10.1242/dev.126.21.4895. View

Alva J, Iruela-Arispe M . Notch signaling in vascular morphogenesis. Curr Opin Hematol. 2004; 11(4):278-83. DOI: 10.1097/01.moh.0000130309.44976.ad. View

Burri P, Tarek M . A novel mechanism of capillary growth in the rat pulmonary microcirculation. Anat Rec. 1990; 228(1):35-45. DOI: 10.1002/ar.1092280107. View

Gonzalez-Mariscal L, Betanzos A, Nava P, Jaramillo B . Tight junction proteins. Prog Biophys Mol Biol. 2002; 81(1):1-44. DOI: 10.1016/s0079-6107(02)00037-8. View

10.

Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio P . Sema4D induces angiogenesis through Met recruitment by Plexin B1. Blood. 2005; 105(11):4321-9. DOI: 10.1182/blood-2004-07-2885. View

11.

van Royen N, Piek J, Buschmann I, Hoefer I, Voskuil M, Schaper W . Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease. Cardiovasc Res. 2001; 49(3):543-53. DOI: 10.1016/s0008-6363(00)00206-6. View

12.

Byrd N, Grabel L . Hedgehog signaling in murine vasculogenesis and angiogenesis. Trends Cardiovasc Med. 2004; 14(8):308-13. DOI: 10.1016/j.tcm.2004.09.003. View

13.

Kluk M, Hla T . Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. Biochim Biophys Acta. 2002; 1582(1-3):72-80. DOI: 10.1016/s1388-1981(02)00139-7. View

14.

Puri M, Partanen J, Rossant J, Bernstein A . Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development. Development. 1999; 126(20):4569-80. DOI: 10.1242/dev.126.20.4569. View

15.

Isogai S, Horiguchi M, Weinstein B . The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol. 2001; 230(2):278-301. DOI: 10.1006/dbio.2000.9995. View

16.

Bogers A, Gittenberger-de Groot A, Poelmann R, Peault B, Huysmans H . Development of the origin of the coronary arteries, a matter of ingrowth or outgrowth?. Anat Embryol (Berl). 1989; 180(5):437-41. DOI: 10.1007/BF00305118. View

17.

Lindahl P, Johansson B, Leveen P, Betsholtz C . Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997; 277(5323):242-5. DOI: 10.1126/science.277.5323.242. View

18.

Sims D . The pericyte--a review. Tissue Cell. 1986; 18(2):153-74. DOI: 10.1016/0040-8166(86)90026-1. View

19.

Fong G, Rossant J, Gertsenstein M, Breitman M . Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 1995; 376(6535):66-70. DOI: 10.1038/376066a0. View

20.

Latker C, Kuwabara T . Regression of the tunica vasculosa lentis in the postnatal rat. Invest Ophthalmol Vis Sci. 1981; 21(5):689-99. View