Esmolol Hydrochloride for Management of the Cardiovascular Stress Responses to Laryngoscopy and Tracheal Intubation

Overview

Journal Br J Anaesth

Publisher Elsevier

Specialty Anesthesiology

Date 1992 May 1

PMID 1642945

Citations 14

Authors

M Vucevic

G M Purdy

F R Ellis

Affiliations

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Abstract

In a double-blind, randomized, controlled prospective study, 30 grade ASA I/II patients received a continuous i.v. infusion of normal saline or esmolol hydrochloride before induction of anaesthesia and tracheal intubation. Arterial pressure and heart rate were measured to assess the pressor response to laryngoscopy and intubation. The heart rate decreased in the esmolol group before induction of anaesthesia. The pressor response to laryngoscopy was significantly less marked in the esmolol group.

Citing Articles

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Perioperative beta-blockers for preventing surgery-related mortality and morbidity in adults undergoing non-cardiac surgery.

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Efficacy of a Bolus Dose of Esmolol and Bolus Dose of Lignocaine for Attenuating the Pressor Response to Laryngoscopy and Endotracheal Intubation in General Anesthesia: A Comparative Study.

Mulimani S, Talikoti D, Vastrad V, Sorganvi V Anesth Essays Res. 2019; 13(2):292-296.

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A Comparison of the Effects of Dexmedetomidine and Propofol in Controlling the Hemodynamic Responses after Intubation: A Double-Blind, Randomized, Clinical Trial Study.

Kamali A, Taghizadeh M, Esfandiar M, Shams Akhtari A Open Access Maced J Med Sci. 2018; 6(11):2045-2050.

PMID: 30559858 PMC: 6290445. DOI: 10.3889/oamjms.2018.385.