Does Repeated Surgery Improve the Prognosis of Colorectal Liver Metastases?

Overview

Journal J Gastrointest Surg

Specialty Gastroenterology

Date 2005 Dec 22

PMID 16368485

Citations 19

Authors

Zenichi Morise

Atsushi Sugioka

Junko Fujita

Sojun Hoshimoto

Takazumi Kato

Akitake Hasumi

Takashi Suda

Hiromichi Negi

Yoshinobu Hattori

Harunobu Sato

Kotaro Maeda

Affiliations

Soon will be listed here.

Abstract

Hepatic resection for colorectal metastases was performed for 188 patients. Overall survival rates after the first hepatectomy are 41.4% and 32.7% for 5 and 10 years, respectively. The survival rate of 116 cases with unilobar hepatic metastases (H1) is significantly higher than those of 48 cases with two to four bilobar metastases (H2) and 24 cases with more than four (H3), respectively. However, the differences between the survival rates from H1 with multiple metastases, H2, and H3 are not significant, even though the H3 group has no 10-year survivors. The 5-year survival rates after the second hepatectomy (30 patients) and the resection of the lung (26 patients) are 30.3% and 35.2%, respectively, in this series. In those patients, the 5-year survival rates from the first metastasectomy are 43.4% and 50.3%, respectively. There are 14 5-year survivors with multiple metastases and 8 of those patients underwent multiple surgeries. There are 13 patients with three or more repeat resections of the liver and/or lung. The 5-year survival rates of the patients from the first and third metastasectomy are 53.9% and 22.5%, respectively. Repeat operations for the liver and the lung contribute to the improving prognosis.

Citing Articles

Appropriate indications for laparoscopic repeat hepatectomy.

Masuda T, Endo Y, Amano S, Kawamura M, Fujinaga A, Kawasaki T BMC Surg. 2023; 23(1):322.

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Laparoscopic Repeat Liver Resection-Selecting the Best Approach for Repeat Liver Resection.

Morise Z, Katsuno H, Kikuchi K, Endo T, Matsuo K, Asano Y Cancers (Basel). 2023; 15(2).

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Results of redo pulmonary metastasectomy.

Ambrogi V, Tamburrini A, Taje R J Thorac Dis. 2021; 13(4):2669-2685.

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Laparoscopic repeat liver resection.

Morise Z Ann Gastroenterol Surg. 2020; 4(5):485-489.

PMID: 33005842 PMC: 7511566. DOI: 10.1002/ags3.12363.

Outcomes of stage IV patients with colorectal cancer treated in a single institution: What is the key to the long-term survival?.

Mukai T, Uehara K, Aiba T, Nakamura H, Ebata T, Nagino M J Anus Rectum Colon. 2019; 2(1):16-24.

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