Bioluminescence Imaging

Overview

Journal Proc Am Thorac Soc

Specialty Pulmonary Medicine

Date 2005 Dec 15

PMID 16352761

Citations 70

Authors

Ruxana T Sadikot

Timothy S Blackwell

Affiliations

Soon will be listed here.

Abstract

Bioluminescence refers to the process of visible light emission in living organisms. Bioluminescence imaging is a powerful methodology that has been developed over the last decade as a tool for molecular imaging of small laboratory animals, enabling the study of ongoing biological processes in vivo. This form of optical imaging is low cost and noninvasive and facilitates real-time analysis of disease processes at the molecular level in living organisms. In this article, we provide a brief introduction to bioluminescence imaging technology and discuss its applications in mouse models of lung inflammation/injury, bacterial pneumonia, and tumor growth and metastasis.

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