Xenomics

Overview

Journal Genome Res

Specialty Genetics

Date 2005 Dec 13

PMID 16339366

Citations 17

Authors

Enrique Amaya

Affiliations

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Abstract

Xenopus genomics, or Xenomics for short, is coming of age. Indeed, biological insight into processes such as growth factor signaling and patterning of the early embryo is now being gained by combining the value of Xenopus as a model organism for cell and developmental biology with genomic approaches. In this review I address these recent advances and explore future possibilities gained from combining this powerful experimental system with genomic approaches, as well as how our quest to understand basic biological principles will be greatly facilitated though the marriage of Xenopus and genomics.

Citing Articles

The cellular and molecular mechanisms of tissue repair and regeneration as revealed by studies in .

Li J, Zhang S, Amaya E Regeneration (Oxf). 2016; 3(4):198-208.

PMID: 27800170 PMC: 5084359. DOI: 10.1002/reg2.69.

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms.

Love N, Pollak N, Dolle C, Niere M, Chen Y, Oliveri P Proc Natl Acad Sci U S A. 2015; 112(5):1386-91.

PMID: 25605906 PMC: 4321265. DOI: 10.1073/pnas.1417290112.

Carbohydrate metabolism during vertebrate appendage regeneration: what is its role? How is it regulated?: A postulation that regenerating vertebrate appendages facilitate glycolytic and pentose phosphate pathways to fuel macromolecule biosynthesis.

Love N, Ziegler M, Chen Y, Amaya E Bioessays. 2013; 36(1):27-33.

PMID: 24264888 PMC: 3992846. DOI: 10.1002/bies.201300110.

A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis.

Zhang S, Li J, Lea R, Amaya E, Dorey K PLoS One. 2013; 8(11):e79469.

PMID: 24244509 PMC: 3828355. DOI: 10.1371/journal.pone.0079469.

Efficient high-throughput sequencing of a laser microdissected chromosome arm.

Seifertova E, Zimmerman L, Gilchrist M, Macha J, Kubickova S, Cernohorska H BMC Genomics. 2013; 14:357.

PMID: 23714049 PMC: 3701504. DOI: 10.1186/1471-2164-14-357.