Antegrade Continence Enema in the Treatment of Obstructed Defaecation with or Without Faecal Incontinence
Overview
Affiliations
Background: Obstructed defaecation and faecal incontinence are complex functional disorders that pose management challenges. In recent times, the antegrade continence enema (ACE) has been tried both as a primary procedure and as a final resort to avoid a colostomy in patients with a variety of functional problems. The purpose of this study was to evaluate the role of the ACE procedure as a treatment option for adult patients suffering from obstructed defaecation with or without faecal incontinence, some of whom also had slow transit constipation.
Methods: Twenty female patients underwent ACE as an appendicostomy (65%) or caecostomy (35%). The median age was 44 years (range, 20-65 years). The indications were obstructed defaecation with faecal incontinence (65%) and obstructed defaecation alone (35%). Fifteen of these patients were followed for 3-51 months (median, 6 months). Cleveland continence score, bowel score and quality of life score were recorded pre- and postoperatively along with post-procedure complications.
Results: Thirteen (65%) patients were satisfied with the outcome and recorded improvement in their scores while two (10%) remained the same and one (5%) was worse. This latter woman and another patient stopped using their ACE, whilst follow-up data was unavailable for three patients. Minor wound infections were noted in nine patients (45%), of whom one needed drainage of an abscess; the rest settled with antibiotics and dressings. Bowel and Cleveland continence scores improved postoperatively (p<0.001 and p=0.001, respectively) but SF36 scores did not. To date, no patient has had a colostomy following an ACE procedure.
Conclusions: Colostomies can be avoided in patients with obstructed defaecation. There is, however, a need to minimise wound infections which seem to be the most troublesome complication.
Sharma A, Rao S, Kearns K, Orleck K, Waldman S Aliment Pharmacol Ther. 2021; 53(12):1250-1267.
PMID: 33909919 PMC: 8252518. DOI: 10.1111/apt.16369.
Bharucha A, Rao S, Shin A Clin Gastroenterol Hepatol. 2017; 15(12):1844-1854.
PMID: 28838787 PMC: 5693715. DOI: 10.1016/j.cgh.2017.08.023.
Laparoscopic-Assisted Percutaneous Endoscopic Cecostomy (LAPEC) in Children and Young Adults.
Koyfman S, Swartz K, Goldstein A, Staller K J Gastrointest Surg. 2017; 21(4):676-683.
PMID: 28097469 DOI: 10.1007/s11605-016-3353-2.
The antegrade continence enema procedure and total anorectal reconstruction.
Zbar A Gastroenterol Rep (Oxf). 2014; 2(2):126-33.
PMID: 24759342 PMC: 4098662. DOI: 10.1093/gastro/gou008.
Constipation and obstructed defecation.
Steele S, Mellgren A Clin Colon Rectal Surg. 2009; 20(2):110-7.
PMID: 20011385 PMC: 2780173. DOI: 10.1055/s-2007-977489.