[Preventive Surgery for Familial Adenomatous Polyposis Coli]

Overview

Journal Chirurg

Specialty General Surgery

Date 2005 Dec 3

PMID 16323029

Citations 5

Authors

M Kadmon

Affiliations

Soon will be listed here.

Abstract

Familial adenomatous polyposis coli (FAP) may not be considered a single disease entity with standardized guidelines for operative treatment. However, prophylactic colectomy after the manifestation of polyps but prior to the development of colorectal cancer is essential. The optimal timing of prophylactic surgery remains a clinical decision taken independently of mutation analysis. In case of the classic FAP phenotype, restorative proctocolectomy and ileal pouch-anal anastomosis is the procedure of choice. The development of reliable guidelines for attenuated FAP variants requires further evidence from clinical studies on surgical strategy and the advantages of prophylactic surgery over regular endoscopic screening with removal of polyps.

Citing Articles

Functional outcome after pouch-anal reconstruction with primary and secondary mucosectomy for patients with familial adenomatous polyposis (FAP).

Ganschow P, Treiber I, Hinz U, Kadmon M Langenbecks Arch Surg. 2019; 404(2):223-229.

PMID: 30680458 DOI: 10.1007/s00423-018-1747-1.

Postoperative outcome and quality of life after surgery for FAP-associated duodenal adenomatosis.

Ganschow P, Hackert T, Biegler M, Contin P, Hinz U, Buchler M Langenbecks Arch Surg. 2017; 403(1):93-102.

PMID: 29075846 DOI: 10.1007/s00423-017-1625-2.

Residual rectal mucosa after stapled vs. handsewn ileal J-pouch-anal anastomosis in patients with familial adenomatous polyposis coli (FAP)--a critical issue.

Ganschow P, Treiber I, Hinz U, Leowardi C, Buchler M, Kadmon M Langenbecks Arch Surg. 2015; 400(2):213-9.

PMID: 25586093 DOI: 10.1007/s00423-014-1263-x.

The prognosis of clinical course and the analysis of the frequency of the inflammation and dysplasia in the intestinal J-pouch at the patients after restorative proctocolectomy due to FAP.

Banasiewicz T, Marciniak R, Kaczmarek E, Krokowicz P, Paszkowski J, Lozynska-Nelke A Int J Colorectal Dis. 2011; 26(9):1197-203.

PMID: 21559820 PMC: 3158850. DOI: 10.1007/s00384-011-1241-5.

[Regional growth preferences in hereditary, synchronous, and metachronous colorectal carcinomas. Basics of tumor surgery Part II].

Stelzner F Chirurg. 2006; 77(11):1056-60.

PMID: 17072493 DOI: 10.1007/s00104-006-1257-5.

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