Antimicrobial Azaphilones from the Fungus Hypoxylon Multiforme

Overview

Journal Planta Med

Specialty Biology

Date 2005 Dec 2

PMID 16320209

Citations 6

Authors

Dang Ngoc Quang

Toshihiro Hashimoto

Marc Stadler

Niko Radulovic

Yoshinori Asakawa

Affiliations

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Abstract

Four new azaphilones named multiformins A - D together with a known compound 4 : 5:4':5'-tetrahydroxy-1 : 1'-binaphthyl were isolated from the methanolic stromatal extract of the xylariaceous ascomycete Hypoxylon multiforme. Their absolute structures were characterised by 2D-NMR, UV, IR, mass and CD spectroscopy. Multiformins A - D showed strong and apparently non-selective antimicrobial activity.

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