A Randomised Study of "wet Wraps" Versus Conventional Treatment for Atopic Eczema
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Aims: To compare two treatments in common usage for children with atopic eczema: "wet wrap" bandages versus conventional topically applied ointments.
Methods: A total of 50 children (age 4-27 months) with moderate to severe eczema were randomised to one or other treatment. Two research nurses supervised the study. The first gave advice and support, and the second, blinded to the treatment modality being used, scored the change in eczema severity over a period of four weeks using the SCORAD eczema severity scale.
Results: Both treatments gave a benefit in overall SCORAD scores (mean change for wet wrap group was 53 to 24; for the conventional group, 41 to 17). There was no significant difference between the two groups in terms of overall improvement at four weeks or in the timescale of improvements. The amount of topical of topical steroid used was similar in both groups. The wet wrap group suffered significantly more skin infections requiring antibiotics. Carers reported that wet wraps were less easy to apply than conventional treatment.
Nonprescription Treatment Options.
Edwards T, Felix K, Francois S, Cardwell L, Rice Z Adv Exp Med Biol. 2024; 1447:151-167.
PMID: 38724792 DOI: 10.1007/978-3-031-54513-9_14.
Strategies for using topical corticosteroids in children and adults with eczema.
Lax S, Harvey J, Axon E, Howells L, Santer M, Ridd M Cochrane Database Syst Rev. 2022; 3:CD013356.
PMID: 35275399 PMC: 8916090. DOI: 10.1002/14651858.CD013356.pub2.
Safety of topical corticosteroids in atopic eczema: an umbrella review.
Axon E, Chalmers J, Santer M, Ridd M, Lawton S, Langan S BMJ Open. 2021; 11(7):e046476.
PMID: 34233978 PMC: 8264889. DOI: 10.1136/bmjopen-2020-046476.
He H, Koh M, Lee H, Ang S Pediatr Dermatol. 2019; 37(1):52-57.
PMID: 31667901 PMC: 7028028. DOI: 10.1111/pde.13981.
Siegfried E, Jaworski J, Mina-Osorio P Dermatol Ther (Heidelb). 2018; 8(3):349-377.
PMID: 29858763 PMC: 6109028. DOI: 10.1007/s13555-018-0243-4.