Inflammatory Pseudotumor in the Epidural Space of the Thoracic Spine: a Case Report and Literature Review of MR Imaging Findings

Overview

Journal AJNR Am J Neuroradiol

Specialty Neurology

Date 2005 Nov 16

PMID 16286421

Citations 8

Authors

Ho Jun Seol

Sam Soo Kim

Ji Eun Kim

Sang Hyung Lee

Jun Yeon Won

Affiliations

Soon will be listed here.

Abstract

We present a rare case of pathologically proven inflammatory pseudotumor in the thoracic spine. The lesion showed an isointense signal on T1-weighted images, a heterogeneous iso- and hyperintense signal on T2-weighted images, and strong homogeneous enhancement. There was no evidence of abnormalities in the adjacent bone. Whereas the exact pathogenesis of this lesion is unknown, it has been regarded as an unusual response to insults such as trauma or acute infection, a post-inflammatory reparative process, or low-grade malignancy.

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References

Rahmouni A, Divine M, Mathieu D, Golli M, Dao T, Jazaerli N . Detection of multiple myeloma involving the spine: efficacy of fat-suppression and contrast-enhanced MR imaging. AJR Am J Roentgenol. 1993; 160(5):1049-52. DOI: 10.2214/ajr.160.5.8470574. View

Roberts G, Farrell M, Allcutt D . Spinal inflammatory pseudotumours. Br J Neurosurg. 2001; 15(2):197-8. View

Hsieh P, Lin C . Multicentric plasma cell granuloma of spinal cord meninges. Clin Orthop Relat Res. 1995; (317):188-92. View

Bluemke D, Wang H . Primary spinal cord lymphoma: MR appearance. J Comput Assist Tomogr. 1990; 14(5):812-4. DOI: 10.1097/00004728-199009000-00028. View

Matsumoto S, Hasuo K, Uchino A, Mizushima A, Furukawa T, Matsuura Y . MRI of intradural-extramedullary spinal neurinomas and meningiomas. Clin Imaging. 1993; 17(1):46-52. DOI: 10.1016/0899-7071(93)90013-d. View

Eimoto T, Yanaka M, Kurosawa M, Ikeya F . Plasma cell granuloma (inflammatory pseudotumor) of the spinal cord meninges: report of a case. Cancer. 1978; 41(5):1929-36. DOI: 10.1002/1097-0142(197805)41:5<1929::aid-cncr2820410537>3.0.co;2-s. View

Gilliard C, De Coene B, Lahdou J, Boutsen Y, Noel H, Godfraind C . Cervical epidural pseudotumor and multifocal fibrosclerosis. Case report and review of the literature. J Neurosurg. 2000; 93(1 Suppl):152-6. DOI: 10.3171/spi.2000.93.1.0152. View

Seider M, Cleary K, Van Tassel P, Alexanian R, Schantz S, Frias A . Plasma cell granuloma of the nasal cavity treated by radiation therapy. Cancer. 1991; 67(4):929-32. DOI: 10.1002/1097-0142(19910215)67:4<929::aid-cncr2820670412>3.0.co;2-q. View

Kilinc M, Erturk I, Uysal H, Birler K, Evrenkaya T, Akkalyoncu B . Multiple plasma cell granuloma of the central nervous system: a unique case with brain and spinal cord involvement. Case report and review of literature. Spinal Cord. 2002; 40(4):203-6. DOI: 10.1038/sj.sc.3101271. View

10.

Roberts G, Eldridge P, Mackenzie J . Case report: inflammatory pseudotumour of the spine, with literature review. Br J Neurosurg. 2000; 11(6):570-2. DOI: 10.1080/02688699745754. View

11.

Hsiang J, Moorhouse D, Barba D . Multiple plasma cell granulomas of the central nervous system: case report. Neurosurgery. 1994; 35(4):744-7. DOI: 10.1227/00006123-199410000-00024. View

12.

Han M, Chi J, Kim M, Chang K, Kim K, Yeon K . Fibrosing inflammatory pseudotumors involving the skull base: MR and CT manifestations with histopathologic comparison. AJNR Am J Neuroradiol. 1996; 17(3):515-21. PMC: 8337984. View

13.

Bahadori M, LIEBOW A . Plasma cell granulomas of the lung. Cancer. 1973; 31(1):191-208. DOI: 10.1002/1097-0142(197301)31:1<191::aid-cncr2820310127>3.0.co;2-d. View

14.

Lee M, Epstein F, Rezai A, Zagzag D . Nonneoplastic intramedullary spinal cord lesions mimicking tumors. Neurosurgery. 1998; 43(4):788-94; discussion 794-5. DOI: 10.1097/00006123-199810000-00034. View

15.

Aizawa T, Sato T, Tanaka Y, Kishimoto K, Watanabe M, Kokubun S . Intramedullary plasma cell granuloma in the cervicothoracic spine. Case report. J Neurosurg. 2002; 97(2 Suppl):235-8. DOI: 10.3171/spi.2002.97.2.0235. View

16.

Despeyroux-Ewers M, Catalaa I, Collin L, Cognard C, Loubes-Lacroix F, Manelfe C . Inflammatory myofibroblastic tumour of the spinal cord: case report and review of the literature. Neuroradiology. 2003; 45(11):812-7. DOI: 10.1007/s00234-003-1069-y. View

17.

Jeon Y, Chang K, Suh Y, Jung H, Park S . Inflammatory myofibroblastic tumor of the central nervous system: clinicopathologic analysis of 10 cases. J Neuropathol Exp Neurol. 2005; 64(3):254-9. DOI: 10.1093/jnen/64.3.254. View

18.

Baker L, Goodman S, Perkash I, Lane B, Enzmann D . Benign versus pathologic compression fractures of vertebral bodies: assessment with conventional spin-echo, chemical-shift, and STIR MR imaging. Radiology. 1990; 174(2):495-502. DOI: 10.1148/radiology.174.2.2296658. View