Gastrointestinal Stromal Tumor in a Child and Review of the Literature
Overview
Pediatrics
Authors
Affiliations
Gastrointestinal stromal tumors (GIST) are c-KIT positive neoplasm that occur predominantly in adults. A 13-year-old boy who presented with massive gastrointestinal hemorrhage was subsequently diagnosed with GIST of the stomach. The tumor originated from the lesser curvature with a narrow base and no infiltration into surrounding organs. Two metastatic lesions in the liver were also found. Total excision of the gastric lesion was performed followed by adjuvant imatinib mesylate chemotherapy. He has had no signs of recurrence during 8 months of follow-up. GIST in children are rare and their behavior is notoriously difficult to predict. We report our experience and review the literature.
Laparoscopic resection of a rare gastrointestinal stromal tumor in children.
Lima M, Gargano T, Ruggeri G, Pession A, Mariotto A, Maffi M Springerplus. 2015; 4:73.
PMID: 25717425 PMC: 4336300. DOI: 10.1186/s40064-015-0850-9.
Tran S, Dingeldein M, Mengshol S, Kay S, Chin A Pediatr Surg Int. 2013; 30(4):457-66.
PMID: 24292407 DOI: 10.1007/s00383-013-3432-3.
Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors.
Belinsky M, Rink L, von Mehren M Front Oncol. 2013; 3:117.
PMID: 23730622 PMC: 3656383. DOI: 10.3389/fonc.2013.00117.
Gastrointestinal stromal tumor of the stomach in a child with a 3-year follow-up period-Case report.
Miranda M, Alberti L, Tatsuo E, Picarro C, Rausch M Int J Surg Case Rep. 2011; 2(6):114-7.
PMID: 22096700 PMC: 3199713. DOI: 10.1016/j.ijscr.2011.02.010.
A large gastrointestinal stromal tumor of the duodenum: a case report.
Morcos B, Al-Ahmad F J Med Case Rep. 2011; 5:457.
PMID: 21917160 PMC: 3180710. DOI: 10.1186/1752-1947-5-457.