Experimental Evaluation of Pentas Lanceolata Flowers for Wound Healing Activity in Rats

Overview

Journal Fitoterapia

Publisher Elsevier

Specialties Pharmacology
Rehabilitation Medicine

Date 2005 Oct 21

PMID 16236462

Citations 8

Authors

B S Nayak

B Vinutha

B Geetha

B Sudha

Affiliations

Soon will be listed here.

Abstract

The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg(-1) day(-1) for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.

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