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Triazole-based Monophosphines for Suzuki-Miyaura Coupling and Amination Reactions of Aryl Chlorides

Overview
Journal Org Lett
Specialties Biochemistry
Chemistry
Date 2005 Oct 21
PMID 16235919
Citations 10
Authors
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Abstract

[reaction: see text] A new class of triazole-based monophosphine 1 (ClickPhos) has been prepared via efficient 1,3-dipolar cycloadditions of readily available azides and acetylenes. Palladium complexes derived from these ligands provide highly active catalysts for Suzuki-Miyaura coupling and amination reactions of aryl chlorides.

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