Improvement of Islet Culture with Sericin

Overview

Journal J Biosci Bioeng

Specialties Biochemistry
Biomedical Engineering
Microbiology

Date 2005 Oct 20

PMID 16233694

Citations 9

Authors

Akiko Ogawa

Satoshi Terada

Takanori Kanayama

Masao Miki

Mitsuhiro Morikawa

Toshihisa Kimura

Akio Yamaguchi

Masahiro Sasaki

Hideyuki Yamada

Affiliations

Soon will be listed here.

Abstract

Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerated the proliferation of the rat insulinoma cell line RIN-5F and improved the serum-free culture of rat islets.

Citing Articles

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Study of the Antioxidative Effects of Silk Sericin in Cultures of Murine Retinal Photoreceptor Cells.

Suzuki S, Sakiragaoglu O, Chirila T Molecules. 2022; 27(14).

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Importance of multiple endocrine cell types in islet organoids for type 1 diabetes treatment.

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Silkworm Sericin: Properties and Biomedical Applications.

Kunz R, Costa Brancalhao R, Ribeiro L, Raquel Marcal Natali M Biomed Res Int. 2016; 2016:8175701.

PMID: 27965981 PMC: 5124675. DOI: 10.1155/2016/8175701.

Non-Mulberry and Mulberry Silk Protein Sericins as Potential Media Supplement for Animal Cell Culture.

Sahu N, Pal S, Sapru S, Kundu J, Talukdar S, Singh N Biomed Res Int. 2016; 2016:7461041.

PMID: 27517047 PMC: 4969515. DOI: 10.1155/2016/7461041.